N/A Completed N=29 Randomized Double-blind Treatment

Food Additives Effects on EEG Profiles in College Students With ADHD

Attention Deficit Hyperactivity Disorder

Source: ClinicalTrials.gov NCT03342469 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Sep 2020

Primary outcomePrimary: Mean Power (EEG) During AFC and Placebo Challenge in ADHD and Control Groups — 3.19; 3.09; 3.50; 2.13 Mean Power (microvolts^2) — p=>0.05

Summary

The purpose of this study is to examine the effects of food additives on college students with ADHD. This study could potentially answer an important question which still remains unanswered as to whether certain food additives may be able to cause cognitive and electrical activity changes in college students with and without ADHD. In this context, food additives will be artificial food coloring.

Outcome Measures

Outcome	Result	p-value
PRIMARY Mean Power (EEG) During AFC and Placebo Challenge in ADHD and Control Groups	3.19; 3.09; 3.50; 2.13; 1.96; 1.60	>0.05
PRIMARY Relative Power (EEG) During AFC and Placebo Challenge in ADHD and Control Groups	0.26; 0.25; 0.27; 0.23; 0.19; 0.18	>0.05
PRIMARY ADHD Symptoms During AFC and Placebo Challenge in ADHD and Control Groups	42.06; 41.00; 24.63; 23.81; 23.76; 22.71	>0.05

Eligibility Criteria

Inclusion Criteria

Generally good health
18-24 years old
Currently attending college
Physician's diagnosis of ADHD (unless control participant)
Stable medication dose and frequency for 3 months before the study
Willing to suspend ADHD medication administration on testing day and the day after testing

Exclusion Criteria

Presence of comorbid psychiatric condition other than comorbid depression or anxiety
Autism
Severe asthma requiring past hospitalization
Seizure disorder

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03342469). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.