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N/A N=500 Diagnostic

Assessment of InfraScanner 2000™ in Detecting Subdural and Epidural Hematomas

Head Trauma · Craniocerebral Injuries · Crushing Skull Injury · Head Injuries · Head Injuries, Multiple

Enrolled (actual)
500
Serious AEs
0.0%
Results posted
May 2019
Primary outcome: Primary: Sensitivity of InfraScanner 2000 TM to Detect Any Size Hematoma at the Patient Level — 85.6 percentage

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
InfraScanner 2000™ (Device)
Age
Pediatric, Adult, Older Adult
Sex
All
Sponsor
Duke University
Primary completion
May 2018

Outcome Measures

OutcomeResultp-value
PRIMARY
Sensitivity of InfraScanner 2000 TM to Detect Any Size Hematoma at the Patient Level
85.6
PRIMARY
Sensitivity of InfraScanner 2000 TM to Detect Any Size Hematoma at the Scan Level
88.5
PRIMARY
Specificity of InfraScanner 2000 TM for Detection of Any Size Hematoma at the Patient Level
95.7
PRIMARY
Specificity of InfraScanner 2000 TM for Detection of Any Size Hematoma at the Scan Level
95.5
PRIMARY
False Positive Rate of InfraScanner 2000 TM for Detection of Any Size Hematoma at the Patient Level
16.0
PRIMARY
False Positive Rate of InfraScanner 2000 TM for Detection of Any Size Hematoma at the Scan Level
10.1
PRIMARY
False Negative Rate of InfraScanner 2000 TM for Detection of Any Size Hematoma at the Patient Level
3.8
PRIMARY
False Negative Rate of InfraScanner 2000 TM for Detection of Any Size Hematoma at the Scan Level
5.2
SECONDARY
Sensitivity in Identification of Hematomas Within Detection Limits, at the Patient Level
94.2
SECONDARY
Specificity in Identification of Hematomas Within Detection Limits, at the Patient Level
95.7
SECONDARY
Sensitivity for Bleeds Within Detection Limits by Hematoma Type at the Patient Level
100.0; 96.9; 75.0; 100.0
SECONDARY
False Negative Value for Bleeds Within Detection Limits by Hematoma Type at the Patient Level
0.0; 0.5; 0.8; 0.0
SECONDARY
Sensitivity for Bleeds Within Detection Limits by Hematoma Type at the Scan Level
90.9; 98.3; 88.0; 96.2
SECONDARY
False Negative Value for Bleeds Within Detection Limits by Hematoma Type at the Scan Level
0.3; 0.5; 0.8; 0.3

Summary

The goal of this study is to determine the sensitivity, specificity, and positive and negative predictive values of the a portable near-infrared-based device (portable NIR-based device), the InfraScanner 2000™, to detect intracranial hematomas (epidural hematomas (EDH) and/or subdural hematomas (SDH)) in patients hospitalized at Duke University Hospital (DUH) who have sustained or who are suspected to have sustained head trauma and have consequently received a brain computed tomography (CT) scan(s).

Eligibility Criteria

Inclusion Criteria

  • Any patient who presents to Duke University Hospital with suspected head trauma and receives a brain CT scan will be considered for this study.

Exclusion Criteria

  • None
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03353246). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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