N/A
Completed N=53
Web-based Addiction Treatment: Cultural Adaptation With American Indians
Source: ClinicalTrials.gov NCT03363256 ↗Enrolled (actual)
53
Serious AEs
1.9%
Results posted
May 2026
Primary outcomePrimary: Consecutive Weeks of Drug/Alcohol Abstinence — 2.0; 2.0 Weeks — p=0.437
Summary
The purpose of the current study is to evaluate the preliminary efficacy of the Therapeutic Education System-Native Version (TES-NAV) (an efficacious web-delivered psychosocial intervention for substance use disorders adapted with American Indians/Alaska Natives [AI/AN]) to determine whether a future large-scale effectiveness trial is warranted. Specifically, a randomized controlled trial among urban AI/AN (N=80) attending outpatient addiction treatment services will be conducted to (1) estimate preliminary effect size of 12 weeks of TES-NAV on substance use disorder outcomes; (2) explore relevant moderators of TES-NAV outcomes; and (3) assess cultural factors that may correspond to variation in outcome.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Consecutive Weeks of Drug/Alcohol Abstinence |
2.0; 2.0 | 0.437 |
Eligibility Criteria
Inclusion Criteria
- 18 years of age or older
- Identify as American Indian or Alaska Native
- Recent alcohol or drug use
- Within first 30 days of current outpatient treatment episode
Exclusion Criteria
- Planned treatment episode of less than 3 months
- Insufficient ability to provide informed consent
Data sourced from ClinicalTrials.gov (NCT03363256). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.