N/A N=53 Randomized Treatment

Web-based Addiction Treatment: Cultural Adaptation With American Indians

Substance Use Disorders

Bottom Line

View on ClinicalTrials.gov: NCT03363256 ↗

Enrolled (actual)

Serious AEs

1.9%

Results posted

May 2026

Primary outcome: Primary: Consecutive Weeks of Drug/Alcohol Abstinence — 2.0; 2.0 Weeks — p=0.437

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: TES-NAV (Behavioral); TAU (Behavioral)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: New York State Psychiatric Institute
Primary completion: Jun 2020

Outcome Measures

Outcome	Result	p-value
PRIMARY Consecutive Weeks of Drug/Alcohol Abstinence	2.0; 2.0	0.437

Summary

The purpose of the current study is to evaluate the preliminary efficacy of the Therapeutic Education System-Native Version (TES-NAV) (an efficacious web-delivered psychosocial intervention for substance use disorders adapted with American Indians/Alaska Natives [AI/AN]) to determine whether a future large-scale effectiveness trial is warranted. Specifically, a randomized controlled trial among urban AI/AN (N=80) attending outpatient addiction treatment services will be conducted to (1) estimate preliminary effect size of 12 weeks of TES-NAV on substance use disorder outcomes; (2) explore relevant moderators of TES-NAV outcomes; and (3) assess cultural factors that may correspond to variation in outcome.

Eligibility Criteria

Inclusion Criteria

18 years of age or older
Identify as American Indian or Alaska Native
Recent alcohol or drug use
Within first 30 days of current outpatient treatment episode

Exclusion Criteria

Planned treatment episode of less than 3 months
Insufficient ability to provide informed consent

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03363256). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.