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N/A N=89 Randomized Quadruple-blind Treatment

Effect of Acupuncture on Patient Vulvodynia Outcomes

Vulvodynia · Vulvodynia, Generalized · Vulvar Vestibulitis

Enrolled (actual)
89
Serious AEs
0.0%
Results posted
May 2025
Primary outcome: Primary: Average Pain Intensity Will be Measured With the Pain Intensity Numbers Scale (PINS). — 3.90; 3.51; 2.48; 2.22 score on a scale — p=0.702

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Active Acupuncture (Other); Placebo Acupuncture (Other)
Age
Adult · 18+ yrs
Sex
Female
Sponsor
University of Illinois at Chicago
Primary completion
Oct 2022

Outcome Measures

OutcomeResultp-value
PRIMARY
Average Pain Intensity Will be Measured With the Pain Intensity Numbers Scale (PINS).
3.90; 3.51; 2.48; 2.22 0.702
SECONDARY
Dyspareunia Subscale of the Female Sexual Function Index (FSFI)
1.22; 1.38; 1.61; 1.83 0.77
SECONDARY
Total Score of the Female Sexual Function Index (FSFI)
15.9; 17.4; 17.0; 19.3 0.436
SECONDARY
Vulvar Pain Intensity Will be Measured With the Pain Intensity Numbers Scale (PINS).
4.19; 2.60; 3.37; 3.68; 3.79; 3.16 0.017 sig

Summary

This study evaluates acupuncture for the treatment of vulvodynia; specifically if it reduces vulvar pain and pain with intercourse. It also examines how long the effect of acupuncture lasts in women with vulvodynia. Half of the women will receive acupuncture and the other half will receive placebo acupuncture. Women who get a reduction in pain will monitor there pain once a week for up to 12 weeks to see how long the acupuncture effect lasts.

Eligibility Criteria

Inclusion Criteria

  • a previous diagnosis of generalized vulvodynia or provoked vestibulodynia
  • 18 to 45 years old
  • a pain now score 4 or higher with tampon insertion and removal performed at the initial screening exam
  • speak and read English

Exclusionary Criteria

  • infectious conditions of the vulva/vagina
  • inflammatory conditions of the vulva/vagina
  • neoplastic disorders of the vulva/vagina
  • neurologic disorders of the vulva/vagina
  • trauma to the genitals
  • iatrogenic conditions of the genitals
  • hormonal deficiencies
  • co-morbid pelvic pain conditions (to avoid confounding pain outcomes) such as pelvic inflammatory disease and documented history of endometriosis
  • menopause

Patients may have a history of but not have active in the last 6 months migraine headaches, temporomandibular joint disease (TMJ), irritable bowel syndrome (IBS), interstitial cystitis, painful bladder syndrome, or fibromyalgia.

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View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03364127). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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