N/A
Completed N=50
Stress and CKD Among African Americans
Source: ClinicalTrials.gov NCT03387319 ↗Enrolled (actual)
50
Serious AEs
0.0%
Results posted
May 2020
Primary outcomePrimary: Change in Subjective Units of Distress Scale (SUDS) Score — 2.92; 3.12 score on a scale
Summary
The goal of this study is to determine whether experiencing stress from discrimination may increase chronic kidney disease (CKD) progression in African Americans. Study participation occurs over the course of 2 days, and participant time burden is expected to be about 4.5 hours, plus a 24-hour period of wearing a blood pressure monitor.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Subjective Units of Distress Scale (SUDS) Score |
2.92; 3.12 | — |
| PRIMARY Change in Cooper's Racism Recall Scale Score |
6.24; 5.48 | — |
| PRIMARY Change in Monocyte Chemoattractant Protein-1 (MCP-1) Level |
193.12; 217.31 | — |
| PRIMARY Change in Interleukin-6 (IL-6) Level |
2.23; 2.11 | — |
| PRIMARY Change in Soluble Urokinase-type Plasminogen Activator Receptor (suPAR) Level |
4.18; 4.50 | — |
| PRIMARY Change in Systolic Blood Pressure |
11.79; 15.72 | — |
| PRIMARY Change in Diastolic Blood Pressure |
5.52; 7.59 | — |
Eligibility Criteria
Inclusion Criteria
- Patient at Emory University Hospital Midtown
- Self-identify as African American or Black
- Estimated glomerular filtration rate (eGFR) ≥ 15, or <90
Exclusion Criteria
- Mental disorder that prevents the completion of the Computer Assisted Personal Interview (CAPI) and the stressful recall manipulation
- Currently on maintenance dialysis
- Unable or unwilling to undergo intravenous catheterization
Data sourced from ClinicalTrials.gov (NCT03387319). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.