N/A
Completed N=72
Acupuncture Treatment of Chronic Obstructive Pulmonary Disease (COPD) Exacerbation
Source: ClinicalTrials.gov NCT03398213 ↗Enrolled (actual)
72
Serious AEs
0.0%
Results posted
Aug 2020
Primary outcomePrimary: Dyspnea Intensity — 8.0; 6.5; 7.75; 5 units on a scale
Summary
Chronic obstructive pulmonary disease (COPD) is a major health problem. Acute exacerbations are a health-care burden involving frequent hospitalizations and elevated costs. They have effective therapies with significant side effects. Acupuncture has been shown to reduce dyspnea and other COPD-related symptoms. The investigators will compare the efficacy and safety of the addition of true acupuncture to usual care with both sham-acupressure added to usual care and usual care only for the treatment of acute exacerbations of COPD among inpatients.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Dyspnea Intensity |
8.0; 6.5; 7.75; 5; 6; 7 | — |
| SECONDARY Duration of Hospitalization |
5.5; 6.0; 6.3 | — |
| SECONDARY Carbon Dioxide Partial Pressure (pCO2) |
6; 3; 8; 12; 17; 9 | — |
| SECONDARY Power of Hydrogen (pH) |
0; 0; 0; 5; 4; 1 | — |
| SECONDARY Respiratory Rate |
21; 22; 20; 16; 18; 21 | — |
| SECONDARY Oxygen Saturation |
4; 1; 0; 9; 10; 10 | — |
| SECONDARY Cough Intensity |
7.5; 5.0; 5.0; 4.5; 5; 5 | — |
| SECONDARY Sputum Intensity |
6.0; 6.0; 5.0; 2.8; 5.5; 4.5 | — |
Eligibility Criteria
Inclusion Criteria
- Previous diagnosis of COPD
- Clinical diagnosis of acute exacerbation of COPD
- Informed consent
Exclusion Criteria
- Hemodynamic instability
- Platelet count < 20 x 10^9/L
- Expected respiratory deterioration requiring mechanical ventilation in the next 24 hours
Data sourced from ClinicalTrials.gov (NCT03398213). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.