N/A
N=76
A Pilot Intervention to Improve Coping With Discrimination and Adherence Among HIV-Positive Latino MSM
HIV
Bottom Line
View on ClinicalTrials.gov: NCT03432819 ↗Enrolled (actual)
76
Serious AEs
0.0%
Results posted
Feb 2021
Primary outcome: Primary: Continuous Adherence (MEMS) — 86.7; 79.0; 85.5; 79.7 % of doses taken, past month — p=0.06
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Siempre Seguiré (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- Male
- Sponsor
- RAND
- Primary completion
- Sep 2019
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Continuous Adherence (MEMS) |
86.7; 79.0; 85.5; 79.7 | 0.06 |
| PRIMARY Continuous Adherence (Self-report) |
97.48; 94.57; 99.17; 92.91 | 0.02 sig |
| SECONDARY Functional Coping Strategies |
2.75; 2.68; 2.82; 2.74 | 0.39 |
| SECONDARY Positive Religious Coping Strategies |
1.84; 2.08; 1.72; 2.08 | 0.54 |
| SECONDARY Dysfunctional Coping Strategies |
2.05; 2.09; 2.06; 2.09 | 0.81 |
| SECONDARY Negative Religious Coping Strategies |
0.17; 0.34; 0.22; 0.30 | 0.06 |
| SECONDARY Medical Mistrust (General) |
2.34; 2.78; 2.28; 2.88 | 0.16 |
| SECONDARY Medical Mistrust (HIV Conspiracy Beliefs) |
1.81; 2.26; 1.90; 2.40 | 0.02 sig |
| SECONDARY Internalized Stigma (Sexual Orientation) |
1.53; 1.59; 1.68; 1.59 | 0.71 |
| SECONDARY Internalized Stigma (HIV) |
2.38; 2.38; 2.14; 2.65 | 0.10 |
Summary
R34-funded study to pilot test an intervention to improve coping with discrimination and adherence among Latino men who have sex with men (MSM) living with HIV. The proposed research aims to modify and refine Siempre Seguiré, a culturally congruent cognitive behavior therapy group intervention for HIV-positive Latino men who have sex with men (LMSM), to include strategies for ART adherence and retention in HIV care; and to conduct a small randomized pilot of Siempre Seguiré to examine feasibility and acceptability, as well as to explore preliminary effects on coping responses to discrimination and antiretroviral treatment adherence among LMSM living with HIV.
Eligibility Criteria
Inclusion Criteria
- Age 18 years-old or older, HIV-positive, biologically male at birth and continue to identify as male, identify as Latino, report having sex with men in the past 12 months, and prescribed ART.
Exclusion Criteria
- Being unwilling or unable to provide informed consent; having mental health problems that require immediate treatment (e.g., psychotic symptoms) or a diagnosed mental disorder that would limit ability to participate (e.g., dementia); and cognitive impairments that result in limited ability to provide informed consent.
Data sourced from ClinicalTrials.gov (NCT03432819). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.