N/A
Completed N=15
Non-invasive Brain Stimulation (NIBS) and Dual-task Walking After Stroke
Source: ClinicalTrials.gov NCT03442868 ↗Enrolled (actual)
15
Serious AEs
0.0%
Results posted
Nov 2020
Primary outcomePrimary: Change in Gait Speed — -0.49; -0.80; 5.49 m/s
Summary
The study aims to identify neural locus critical for dual-task walking (walking and talking) in individuals with stroke. To achieve this aim, the investigators apply repetitive transcranial magnetic stimulation (rTMS) to different parts of the brain and evaluate the effects of brain stimulation on dual-task walking speed.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Gait Speed |
-0.49; -0.80; 5.49 | — |
| SECONDARY Change in Step Lengths |
2.24; 1.38 | — |
| SECONDARY Change in Single Support Times |
0.63; 2.50 | — |
| SECONDARY Change in Counting Task Performance |
-0.18; -0.59; -0.65 | — |
Eligibility Criteria
Inclusion Criteria
- Age above 18 years
- Diagnosis of Left hemispheric stroke at least 6 months ago
- First time stroke OR complete gait recovery from prior stroke
- Able to walk independently for at least 10 meters with or without walking aids
- Have at least minimal movements (> 5 degree of motion) at the affected ankle
- Score > 26 on Mini Mental State Exam (MMSE)
- Ability to participate in the informed consent process
Exclusion Criteria
- Diagnosis of other neurological conditions, such as Parkinson Disease, Alzheimer, Spinal Cord Injury, Multiple Sclerosis
- Other comorbidities which could interfere with gait (i.e. amputation, severe osteoarthritis)
- Unstable clinical conditions
- Non-ambulatory prior to onset of stroke
- History of significant head trauma
- Electrical, magnetic, or mechanical implantation: cardiac pacemakers or intracerebral vascular clip
- Metal implantation in the oral cavity, head/neck area and lower extremity
- Pregnancy
- History of seizures or unexplained loss of consciousness
- Immediate family member with epilepsy
- Use of seizure threshold lowering medicine
- Current abuse of alcohol or drugs
- Anticipated inability to complete the study
- History of psychiatric illness requiring medication control
Data sourced from ClinicalTrials.gov (NCT03442868). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.