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Phase 4 N=78 Randomized Quadruple-blind Treatment

Prevention of Persistent Opioid Use in Mothers

Opioid Use · Postpartum Disorder · Chronic Pain Syndrome

Enrolled (actual)
78
Serious AEs
0.0%
Results posted
Nov 2021
Primary outcome: Primary: Time to Opioid Cessation as a Measure of Opioid Utilization — 2; 2 weeks

Study Design & Population

Study type
Interventional
Phase
Phase 4
Interventions
Gabapentin (Drug); Placebo (Drug)
Age
Adult, Older Adult · 18+ yrs
Sex
Female
Sponsor
Stanford University
Primary completion
Jul 2020

Outcome Measures

OutcomeResultp-value
PRIMARY
Time to Opioid Cessation as a Measure of Opioid Utilization
2; 2
SECONDARY
Pain Report
7; 12
SECONDARY
Functional Recovery
8; 11

Summary

Our previous work has identified the group of women at risk for prolonged pain, opioid use and poor functional recovery after childbirth. The optimal intervention to mitigate this risk is unknown. We propose to test an analgesic adjutant that is commonly used for post-operative pain compared to placebo to improve post-partum recovery.

Eligibility Criteria

Inclusion Criteria

  • Delivery within 5 days, able to provide informed consent, English speaker

Exclusion Criteria

  • Opiate use disorder
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03472521). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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