N/A
Completed N=160
Neurobehavioral Plasticity to Regular Sugar-Sweetened Beverage Intake: An fMRI Experiment
Source: ClinicalTrials.gov NCT03490734 ↗Enrolled (actual)
160
Serious AEs
0.0%
Results posted
Apr 2023
Primary outcomePrimary: Change in Voxel-wise Blood Oxygen Level Dependent (BOLD) Including Outliers Using Functional Magnetic Resonance Imaging (fMRI) of Brain Activation Signals in Response to Beverage Taste and Logo — -2.69; -3.06 arbitrary units — p=0.52
Summary
The proposed project will examine the strength, specificity and persistence of neurobehavioral adaptions that occur in the initial period of repeated consumption of a branded sugar sweetened beverage (SSB).
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Voxel-wise Blood Oxygen Level Dependent (BOLD) Including Outliers Using Functional Magnetic Resonance Imaging (fMRI) of Brain Activation Signals in Response to Beverage Taste and Logo |
-2.69; -3.06 | 0.52 |
| SECONDARY Change in Voxel-wise Blood Oxygen Level-Dependent (BOLD) Brain Activation in Response to Beverage Taste and Logo by Body Mass Index (BMI) |
3.47; -9.82 | 0.016 sig |
| SECONDARY Beverage Perceptual Ratings Using Visual Analog Scales |
25.00; -21.00; 24.20; -8.84; 20.30; -23.70 | — |
| SECONDARY Stop Signal Reaction Time to Logo as Measured by Behavioral Response Inhibition Task |
0.5321; 0.5452; 0.5013; 0.5360 | — |
Eligibility Criteria
Inclusion Criteria
- Potential participants will be eligible for the study if they have BMI scores between the 18 and 34 at baseline.
Exclusion Criteria
- Individuals with probable current Axis I psychopathology or any fMRI contra-indicators (e.g., metal implants, braces) will be excluded. Those with a probable Axis I diagnosis will be provided with treatment referral information and encouraged to seek treatment,
- current regular use (3 or more times a week) of psychoactive drugs (e.g., cocaine, marijuana, nicotine),
- regular smoking,
- serious medical problems (e.g., cancer, diabetes),
- dietary practices that do not allow intake of intervention beverages.
Data sourced from ClinicalTrials.gov (NCT03490734). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.