N/A
N=25
Transcranial Direct Current Stimulation (tDCS) and Intensive Therapy in Aphasia
Aphasia
Bottom Line
View on ClinicalTrials.gov: NCT03510182 ↗Enrolled (actual)
25
Serious AEs
0.0%
Results posted
Sep 2021
Primary outcome: Primary: Change in Controlled Oral Word Fluency — 3.1 number of words
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- transcranial direct current stimulation (Device)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of Michigan
- Primary completion
- Feb 2020
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Controlled Oral Word Fluency |
3.1 | — |
| PRIMARY Change in Boston Naming Score |
1.25 | — |
| SECONDARY Change in Western Aphasia Quotient Score |
8.57 | — |
Summary
Intensive therapy for aphasia has been demonstrated to improve language functioning after stroke or other neurological injury. However, recovery is generally not complete and new therapies are needed to improve outcomes. Transcranial direct current stimulation (tDCS) has been shown to improve outcomes with motor therapy after stroke. This study will examine the feasibility of using tDCS with intensive language therapy as a way of enhancing language outcomes in aphasia
Eligibility Criteria
Inclusion Criteria
- Diagnosis of aphasia
- Enrolled in intensive therapy program at the University of Michigan Aphasia Program.
- Ability to understand and give consent to treatment.
Exclusion Criteria
- No metal implants or surgical devices
- History of seizures
- History of significant cognitive or psychiatric disturbance
- Participant cannot be pregnant at the time of study
Data sourced from ClinicalTrials.gov (NCT03510182). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.