N/A
N=140
Walking and mHealth to Increase Participation in Parkinson Disease
Parkinson Disease
Bottom Line
View on ClinicalTrials.gov: NCT03517371 ↗Enrolled (actual)
140
Serious AEs
22.9%
Results posted
Mar 2025
Primary outcome: Primary: Walking Activity — -207.59; -135.24 change in average daily steps — p=.89
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- mHealth delivered exercise program (Other); Exercise only (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Boston University Charles River Campus
- Primary completion
- Mar 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Walking Activity |
-207.59; -135.24 | .89 |
| PRIMARY Walking Intensity |
1.67; 1.33 | .42 |
| SECONDARY Walking Capacity - Six Minute Walk Distance |
15.63; 17.79 | .85 |
| SECONDARY Walking Capacity - Ten Meter Walk Test |
.027; .019 | .824 |
Summary
Identifying effective ways to improve function, slow decline and reduce disability is a high priority for people living with Parkinson disease and other chronic conditions. Regular participation in walking is essential to reduce disability and enhance participation in preferred life activities. However, people with chronic conditions are often sedentary, contributing to greater disability. The goal of this work is to determine the benefits of a walking, walking enhancing exercises and cognitive-behavioral strategies delivered using mobile health technology for people with Parkinson disease over a sustained period of time.
Eligibility Criteria
Inclusion Criteria
- Diagnosis of idiopathic, typical Parkinson disease according to the UK Brain Bank Criteria;
- Hoehn & Yahr stages 1-3 (mild to moderate disease severity);
- Stable on all PD medications for at least 2 weeks prior to study entry;
- Willing and able to provide informed consent.
Exclusion Criteria
- 2 on item 7 of the new freezing of gait questionnaire (moderately or significantly disturbing freezing episodes during daily walking);
- significant cognitive impairment;
- unstable medical or concomitant illnesses or psychiatric conditions, which in the opinion of the investigators would preclude successful participation;
- cardiac problems that interfere with ability to safely exercise
- orthopedic problems in the lower extremities or spine that may limit walking distance;
- unable to walk for 10 continuous minutes independently;
- live in an institution or medical facility (i.e. not in the community)
Data sourced from ClinicalTrials.gov (NCT03517371). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.