N/A
Completed N=45
Adjunctive Steps for Disinfection of Teeth With Primary Endodontic Infections
Periapical Periodontitis · Bacterial Infections
Source: ClinicalTrials.gov NCT03537664 ↗
Enrolled (actual)
45
Serious AEs
—
Results posted
Oct 2020
Primary outcomePrimary: Metabolic Activity of Persistent Bacteria — 4.748; 2.57; 2.614; 4.0008 RNA/DNA ratio
Summary
This study aims to evaluate an endodontic treatment protocol using adjunctive steps for disinfection of teeth with primary endodontic infections.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Metabolic Activity of Persistent Bacteria |
4.748; 2.57; 2.614; 4.0008; 3.7875; 1.136 | — |
| SECONDARY Bacterial Levels |
178500; 7580; 3815; 15550; 0; 0 | — |
| SECONDARY Bacterial Community Diversity |
39.7; 39.8; 39.8; 39; 39.1; 38.6 | — |
Eligibility Criteria
Inclusion Criteria
- Teeth with necrotic pulps and asymptomatic apical periodontitis
Exclusion Criteria
- patients who had received antibiotics during the previous 3 months or had any general disease,
- teeth that could not be properly isolated with rubber dam,
- non-restored teeth,
- periodontal pockets depths greater than 4 mm,
- previous endodontic treatment,
- open apex,
- crown/root fracture
- root resorption or calcifications.
Data sourced from ClinicalTrials.gov (NCT03537664). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.