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N/A Completed N=26 Randomized Double-blind Treatment

Effects of Octacosanol During Taekwondo Training

oxidative stress · Dyslipidemias
Source: ClinicalTrials.gov NCT03557476 ↗
Enrolled (actual)
26
Serious AEs
0.0%
Results posted
Aug 2019
Primary outcomePrimary: Triglycerides — 34.9; 110 mg/dL

Summary

Taekwondo players undergo rapid reductions of body weight prior to their competition in order to gain a size advantage over the opponent. However, these large weight changes with concomitant high intensity exercise training induce poor lipid profiles and high levels of oxidative stress, which can be detrimental to health and sports performance. Therefore, the purpose of this study was to investigate the ability of the nutritional supplement octacosanol to combat the physiological detriments that can occur from these rapid weight changes paired with high intensity exercise training.

Outcome Measures

OutcomeResultp-value
PRIMARY
Triglycerides
34.9; 110
PRIMARY
Total Cholesterol
164; 173.5
PRIMARY
High-density Lipoprotein
71; 49.2
PRIMARY
Low-density Lipoprotein
92.6; 114.9
SECONDARY
Malondialdehyde
0.25; 0.93
SECONDARY
Superoxide Dismutase
1450; 1010
SECONDARY
Glutathione Peroxidase
66.9; 47.1

Eligibility Criteria

Inclusion Criteria

  • at least 3 years of experience in national taekwondo competitions
  • abstain from caffeinated drinks, alcohol, and antioxidant supplements during the whole period of the study

Exclusion Criteria

  • no history of chronic use of antioxidants, chronic aspirin, and nonsteroidal anti-inflammatory drugs (NSAIDs)
  • No cardiovascular, neurological, metabolic or renal diseases
  • no musculoskeletal injuries
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03557476). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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