N/A
N=60
Assesment of Post-stroke Elbow Flexor Spasticity in Different Forearm Positions
Post-stroke Elbow Spasticity
Bottom Line
View on ClinicalTrials.gov: NCT03563209 ↗Enrolled (actual)
60
Serious AEs
0.0%
Results posted
May 2019
Primary outcome: Primary: Dynamic Component of Spasticity (Spasticity Angle) — 70; 60; 57.5 degree — p=<0.001
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- —
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Izmir Katip Celebi University
- Primary completion
- Aug 2018
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Dynamic Component of Spasticity (Spasticity Angle) |
70; 60; 57.5 | <0.001 sig |
Summary
Determination of which muscle is more spastic before injection of the botulinum toxin, and the application of the targeted treatment to that muscle results in more improvement in spasticity. It is known that the muscles that flex elbow in healthy individuals change according to forearm position. While the biceps brachii flexes the forearm in supination, the brachioradialis flexes the forearm in the neutral position. The brachialis muscle acts as a primary flexor muscle when the forearm is in pronation.
In this study, hypothesis is that the severity of spasticity differs depending on the forearm position.
Eligibility Criteria
Inclusion Criteria
- Elbow flexor spasticity
- Grade 1 to 3 spasticity measured with Modified Ashworth Scale
- To agree to participate in the study
Exclusion Criteria
- <18 years old
- Pregnancy
- Botulinum toxin injection within the last three months
- Presence of elbow contracture
- History of operation to spastic upper extremity
- Spasticity due to other causes other than stroke
- Do not agree to participate in the study
Data sourced from ClinicalTrials.gov (NCT03563209). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.