N/A
N=79
mHealth App for Engagement in Care Among Youth Living With HIV
HIV/AIDS · Mobile Health · Young Adults
Bottom Line
View on ClinicalTrials.gov: NCT03587857 ↗Enrolled (actual)
79
Serious AEs
0.0%
Results posted
Jul 2025
Primary outcome: Primary: Feasibility: Rate of Participant Recruitment — 79 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Mobile Health Application (Other)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of California, San Francisco
- Primary completion
- May 2020
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Feasibility: Rate of Participant Recruitment |
79 | — |
| PRIMARY Feasibility: Frequency of WYZ Access |
5.3 | — |
| PRIMARY Feasibility: Length of Session (Minutes) |
8.7 | — |
| PRIMARY Feasibility: Rate of Use of ART Adherence Tracking |
58 | — |
| PRIMARY Feasibility: Rate of Communication With Peers |
4.8 | — |
| SECONDARY Acceptability: Participant Retention |
69 | — |
| SECONDARY Acceptability: Overall App Experience |
53 | — |
| SECONDARY Acceptability: Privacy, Security, and Anonymity |
69 | — |
| SECONDARY Acceptability: Continue Using WYZ |
57 | — |
Summary
In the US, fewer than 6% of all youth living with HIV (YLWH) achieve HIV viral suppression. However, health disparities among youth extend across the entire HIV care continuum in that there is a strong association between younger age and later HIV diagnosis, lower engagement in care, lower levels of antiretroviral therapy (ART) adherence, and worse HIV clinical outcomes. In response to this critical public health dilemma, the investigators propose to develop a novel mobile health application ("app") to improve engagement in health care and ART adherence and to pilot test this mobile health app in 18-29-year-old YLWH residing in San Francisco.
The aims of this study are to:
Aim 1: Build on a theory-guided model and formative work to complete the development of a novel personalized mobile health app for improved HIV clinical outcomes among YLWH (includes field test of initial release to ensure adequate usability and engagement).
Aim 2: Conduct a six-month single arm pilot study to examine WYZ feasibility and acceptability among YLWH ( N = 76) living in the San Francisco Bay Area. Finally, the investigators will conduct in-depth qualitative interviews with a subset of participants (N = 20) and clinical team members (N = 10) whose patients participated in the pilot study.
The investigators hypothesize that this mobile health app will be feasible and acceptable and will result in improved HIV clinical outcomes. Upon completion, the investigators will be ready to test the efficacy of this app in a subsequent large-scale randomized control trial among a population that is disproportionately impacted by HIV and at elevated risk for poor clinical outcomes.
Eligibility Criteria
Eligibility Criteria:
- Must be between 18 and 29 years of age
- Must be living with HIV
- Must reside and/or get care in San Francisco Bay Area
- Must be able to provide informed consent to be a research participant
- Must be able to speak and understand English
- Must have access to an Android (5.0 or higher) or iOS (10.0 or higher) mobile phone
Exclusion Criteria
Evidence of cognitive impairment or psychotic disorder that prevents one from understanding the purpose of the study and/or participating fully in study activities. This determination will be made by trained study staff in consultation with the principal investigator.
Data sourced from ClinicalTrials.gov (NCT03587857). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.