N/A N=16 Randomized Single-blind Treatment

Testing TRUST Depression Management Intervention

Depressive Symptoms · Quality of Life

Bottom Line

View on ClinicalTrials.gov: NCT03599141 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jan 2024

Primary outcome: Primary: Patient Health Questionnaire-8 Adolescent — 6.17; 9.43; 6.80; 8.29 units on a scale

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Trust-building Self-management Together (Behavioral); Depression Management (Behavioral)
Age: Pediatric · 14+ yrs
Sex: All
Sponsor: Case Western Reserve University
Primary completion: Sep 2021

Outcome Measures

Outcome	Result	p-value
PRIMARY Patient Health Questionnaire-8 Adolescent	6.17; 9.43; 6.80; 8.29	—
SECONDARY Youth Quality of Life Scale	71.89; 57.33; 64.93; 61.71	—
SECONDARY Adolescent Sleep Hygiene Scale	4.63; 4.56; 4.73; 4.17	—
SECONDARY Stress Management	14.33; 9.86; 13.40; 12.43	—
SECONDARY Medication Adherence	2.33; 4.67; 2.08; 4.00	—
SECONDARY Appointment Keeping	7.40; 8.67; 7.20; 5.83	—

Summary

This study evaluates the effectiveness of a novel depression self-management intervention in adolescents with depression.

Eligibility Criteria

Inclusion Criteria

Lives in the Cleveland metro area
Ages 14-17 years old
Reports moderate depressive symptoms
Able to read, speak, and understand the English language

Exclusion Criteria

Current suicide risk
Diagnosis with bipolar disorder, schizophrenia, or a personality disorder
Severe behavioral problems that preclude group participation (as reported by parent)
Family plans to move from the region within 6 months

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03599141). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.