N/A
Completed N=26
Transcranial Direct Current Stimulation Therapy for Major Depression
Source: ClinicalTrials.gov NCT03632434 ↗Enrolled (actual)
26
Serious AEs
0.0%
Results posted
Aug 2024
Primary outcomePrimary: Clinical Response — 22 Participants
Summary
Depression is a prevalent and debilitating disorder. The most common treatments are antidepressant medications and talking therapies. However, for many individuals, these are not their treatment of choice. Furthermore, even following a full course of treatment with an antidepressant or talking therapy, over one third of patients continue to be unwell.
The novel brain stimulation treatment, transcranial direct current stimulation (tDCS), is a potential first-line treatment for major depression. The present research question is whether tDCS can be provided as a home-based treatment for major depression for adults with major depression.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Clinical Response |
22 | — |
Eligibility Criteria
Inclusion Criteria
- diagnosis of major depressive disorder based on DSM-5 criteria
- minimum score of 16 on Hamilton Rating Scale for Depression (HAM-D)
Exclusion Criteria
- history of treatment-resistant depression
- comorbid psychiatric disorder
- significant risk of suicide or self harm
- any contraindications to tDCS, including implanted electronic medical devices
Data sourced from ClinicalTrials.gov (NCT03632434). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.