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N/A N=207 Randomized Single-blind Treatment

Group ("Project Life Force") vs. Individual Suicide Safety Planning RCT

Suicide

Enrolled (actual)
207
Serious AEs
29.0%
Results posted
Nov 2025
Primary outcome: Primary: Columbia Suicide Rating Scale (C-SSRS) — 22; 30 participants with an event — p=0.263

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Project Life Force (Behavioral); Treatment as Usual (Behavioral)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
VA Office of Research and Development
Primary completion
Dec 2023

Outcome Measures

OutcomeResultp-value
PRIMARY
Columbia Suicide Rating Scale (C-SSRS)
22; 30 0.263
PRIMARY
Suicidal Behavior by Chart Abstraction
PRIMARY
Death by Suicide by National Death Index Survey Findings
SECONDARY
Beck Depression Inventory-II Change
32.03; 30.90; 23.54; 24.32; 23.82; 25.19 .72
SECONDARY
Beck Hopelessness Scale Change
10.11; 9.40; 7.74; 8.21; 8.18; 7.67 .23
SECONDARY
Suicide-related Coping Scale Change
48.30; 49.17; 53.68; 50.09; 53.15; 49.22 .09
SECONDARY
Outpatient Mental Health Treatment Utilization
17.96; 17.53; 45.28; 37.82 .15
SECONDARY
Drug Abuse Screening Test 10 (DAST-10)
4.0; 3.57 .52
SECONDARY
Alcohol Use Disorders Identification Test-Consumption (AUDIT-C)
1.95; 1.62 .83

Summary

The management of suicide risk is a pressing national public health issue especially among Veterans. This grant consists of two arms: the novel treatment and treatment-as-usual. "Project Life Force" (PLF), a novel suicide safety planning group intervention has been developed to provide a mechanism to develop and enhance the Suicide Safety Plan (SSP) over time. PLF, a 10-session, group intervention, combines cognitive behavior therapy (CBT)/dialectical behavior therapy (DBT) skill based, and psychoeducational approaches, to maximize suicide safety planning development and implementation. Veterans revise their plans over several weeks while learning coping, emotion regulation, and interpersonal skills to incorporate into their safety plans.

Eligibility Criteria

Inclusion Criteria

  • Discharge from inpatient unit for suicidal ideation or attempts, or placement on the high-risk suicide list maintained by suicide prevention coordinators
  • Completion of a safety plan during the past 6 months prior to entry
  • Concurrence from the patient's mental health provider for the Veteran to participate in the study and the provider is willing to work with the research team.

Exclusion Criteria

  • Unable to provide informed consent or complete study requirements
  • Unable to speak English
  • Cognitive difficulties that impair consent capacity
  • Unable or unwilling to provide at least one verifiable contact for emergency or tracking purposes
  • Unable to attend outpatient group treatment program or tolerate group therapy format
  • Active alcohol or opiate dependence requiring medically supervised withdrawal
  • Schizophrenia diagnosis
  • Participation in another intervention RCT
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03653637). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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