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N/A N=34 Randomized Double-blind Health Services Research

Comparison of Pre-op and Post-op Pectoralis Nerve Block

Breast Cancer · Postoperative Pain · Anesthesia · Nerve Block

Enrolled (actual)
34
Serious AEs
0.0%
Results posted
Aug 2024
Primary outcome: Primary: Pain Score Assessment Using a Visual Analog Scale-Immediately Post-surgery — 1.6; 2.3 units on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
PEC I/II blocks by anesthesiologist - pre-operative (Procedure); PEC I/II blocks by surgeon - intra-operative (Procedure)
Age
Adult, Older Adult · 18+ yrs
Sex
Female
Sponsor
Melinda Seering
Primary completion
Oct 2021

Outcome Measures

OutcomeResultp-value
PRIMARY
Pain Score Assessment Using a Visual Analog Scale-Immediately Post-surgery
1.6; 2.3
SECONDARY
Pain Score Assessment-Post-operative Day 1
3.1; 2.7
SECONDARY
Pain Score Assessment-Post-operative Day 3
2.5; 2.1
SECONDARY
Pain Score Assessment-Post-operative Day 7
1.8; 1.9
SECONDARY
Pain Score Assessment Using a Visual Analog Scale-Post-operative Surgical Recheck.
1.7; 1.2
SECONDARY
Measure the Amount of Narcotics Use to Control Pain.
7.5; 8.0
SECONDARY
Measure the Amount of Narcotics Use to Control Pain (In-patient)
30; 25.5
SECONDARY
Measure the Amount of Narcotics Use to Control Pain (Intra-op)
42; 42.4

Summary

The investigators will compare whether patients will have better pain control if they were to receive (PEC I/II block) before surgery or after mastectomy.

Eligibility Criteria

Inclusion Criteria

  • At least 18 years of age
  • Female
  • Bilateral mastectomy for breast cancer
  • Undergoing breast reconstruction
  • Must weigh at least 50 kg

Exclusion Criteria

  • More than 80 years of age
  • Male
  • Prisoners
  • Patients who can't provide their own consent
  • Lumpectomy only patients
  • Patients having prophylactic mastectomies
  • Patient must weigh at least 50 kg
  • Allergies to local anesthetics
  • Patient refusal
  • Patients with a history of bleeding disorders
  • Non-English speaking patients
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03653988). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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