N/A
Completed N=6,544
Online Grammatical Reasoning Training for Older Adults
Healthy Aging
Source: ClinicalTrials.gov NCT03661190 ↗
Enrolled (actual)
6,544
Serious AEs
0.0%
Results posted
May 2026
Primary outcomePrimary: Change in Executive Function From Baseline — 5435.9; 9671.19 score on a scale
Summary
The START study will investigate the impact of playing a Grammatical Reasoning brain training task on overall brain function (cognition) and day-to-day function in people over 50.
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Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Executive Function From Baseline |
5435.9; 9671.19 | — |
| SECONDARY Change in Numerical Working Memory From Six Weeks |
0.55; 0.29 | — |
| SECONDARY Change in Working Memory From Baseline |
1.90; 1.09 | — |
| SECONDARY Change in Reaction Time From Baseline |
10.04; 3.66 | — |
| SECONDARY Change in Episodic Memory From Baseline |
57.9; 45.4 | — |
| SECONDARY Change in Overall Composite Measure of Global Cognition |
0.22; 0.08 | — |
Eligibility Criteria
Inclusion Criteria
- Adults over 50
- Access to a computer with a keyboard and the internet
- Participant registered on the PROTECT study
Exclusion Criteria
- Diagnosis of dementia
Data sourced from ClinicalTrials.gov (NCT03661190). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.