N/A N=50 Maintaining Cognitive Health in Aging Veterans
Healthy People Programs
Primary: Knowledge of Memory Aging Questionnaire-Revised — 19.8; 19.5 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=32 Healthy Aging Through Functional Food
Glucose Intolerance · Aortic Stiffness · Vasodilation
Primary: Area Under the Curve for Oral Glucose Tolerance Test (oGGT) — 10.8; 11.0; 9.9; 10.6 mM h
N/A N=28 Enhancing Well-Being Through Exercise During Old Age
Depression · Osteoarthritis
Primary: Attendance of the Fit & Strong! Intervention Classes — 10 Classes attended
N/A N=69 Exercise for Healthy Aging: The Impact of HIV and Aging on Physical Function and the Somatopause
HIV · Inflammation · Obesity
Primary: Time to Rise From a Chair 10 Times (Modified From the Original Short Physical Performance Battery) — -20; -20; -8; -10 percentage change
N/A N=293 Decision Making and Implementation of Aging-in-Place/Long Term Care Plans Among Older Adults
Alzheimer Disease · Mild Cognitive Impairment · Long-Term Care Planning
Primary: Rate of Participant Long Term Care Planning for Alzheimer's Dementia/Memory Loss — 173 Participants — p=.6539
Phase 2 N=8 Acarbose Anti-aging Effects in Geriatric Subjects (Substudy B & C)
Aging
Primary: Change in Microbiome — 0; 0; 0 Operational Taxonomic Unit (OTU)
Phase 2 N=45 Targeting Inflammation to Treat Cardiovascular Aging
Vascular Stiffness · Endothelial Dysfunction · Diastolic Dysfunction
Primary: Carotid-femoral Pulse Wave Velocity (CFPWV) — 831.3; 785.1; 538.0; 839.6 cm/sec
N/A N=63 Adaptability and Resilience in Aging Adults-2
Aging · Chronic Low-back Pain
Primary: Session-level Engagement — 6.3 score on a scale
N/A N=40 Daily Activity Study of Health: Increasing Physical Activity in Aging
Aging
Primary: Change in Sedentary Behavior (Average Hour/Day) — -0.11; 0.05 Change in average daily hours — p=0.8
N/A N=14 Enhancing Physical Function in the Long-term for Older Adults
Weight Loss Maintenance
Primary: Proportion Retention — 93 percent of participants
N/A N=314 Reducing Cardiometabolic Risk and Promoting Functional Health in Older Adults With Obesity and Prediabetes
Obesity · PreDiabetes · Aging
Primary: Change in Bodyweight — -7.4; -6.1 percentage of bodyweight change — p=0.196
N/A N=90 Exercise Training and Glucose Metabolism in Aging
Type 2 Diabetes Mellitus · Impaired Glucose Tolerance (Prediabetes)
Primary: Baseline Glucose Utilization — 0.0062; 0.0035 µmol/kgFFM/pmol insulin/min
N/A N=71 Long-term Caloric Restriction and Cellular Aging Markers
Aging
Primary: Telomere Length — 0.96; 1.06; 1.06; 1.22 ratio
N/A N=90 Health, Aging and Later-Life Outcomes
Aging
Primary: Number of Participants That Sustained >10% Caloric Restriction — 7; 12 Participants
N/A N=101 Improving Medication Adherence in Older African Americans With Diabetes
Type 2 Diabetes · Mild Cognitive Impairment
Primary: Percent of Participants With Improvement in Hemoglobin A1c by 0.5%" — 25; 22 Participants — p=0.31
N/A N=122 Exercise Effects on Brain Health and Learning From Minutes to Months
Sedentary Lifestyle
Primary: Change in Hippocampal-dependent Learning — -.00369; .00404 learning rate (proportion correct/trial) — p=<.05
N/A N=283 Healthy Aging Resources to Thrive (HART)
Sedentary Lifestyle
Primary: Change in Time Spent Sitting or Lying Down at 6 Months — -40.36; -8.51 Minutes — p=0.003
N/A N=19 Maintaining Autonomy as we Age. Strategy Training for Age-related Executive Dysfunction.
Aging
Primary: Total Number of Goals Improved to Criterion on the Canadian Occupational Performance Measure (COPM) — 50; 19.6; 50; 32.6 percentage of untrained goals improved — p=0.03
N/A N=176 Mindful Movement for Physical Activity and Wellbeing in Older Adults- A Hybrid Effectiveness-Implementation Study
Physical Inactivty · Wellbeing · Mindfulness
Primary: Moderate-Vigorous Physical Activity (MVPA) in 10 Min Bouts — 18.35; 15.54 minutes per week
N/A N=66 Study of the Long-term Effects of Exercise on Heath Indicators in Older People
Hypertension With Complications and Secondary Hypertension · Overweight and Obesity · Lipid Metabolism Disorders
Primary: Cardiovascular Disease Risk Factors — 3; 4; 5; 7 participants
N/A N=50 Activate For Life: mHealth Intervention To Address Pain And Fatigue In Low-income Older Adults Aging In Place
Pain, Chronic · Fatigue Syndrome, Chronic · Aging
Primary: Older Adult Pain Intensity — -3.25; -2.8; -0.5 T-score
N/A N=30 Role of Flavanols In Cardiovascular Function in Healthy Aging
Aging
Primary: Cutaneous Blood Flow Response to Local Heating of the Skin. — 68; 70 percent change in mean skin blood flow
N/A N=977 Aging and Cognitive Health Evaluation in Elders (ACHIEVE)
Aging · Cognitive Decline
Primary: Change in Global Cognitive Function — -0.202; -0.200 score on a scale — p=0.96
N/A N=116 Healthy Me: A Program for Older Women
Obesity
Primary: Weight Change — -2.50; -0.51 percentage of body weight — p=0.008
N/A N=23 Dietary Nitrate and Physiological Aging
Aging
Primary: Change in Carotid Chemosensitivity Following 4 Weeks of Dietary Nitrate Supplementation and Placebo in Older Adults — -0.13; -0.05; -0.10; -0.11 L/min/%SpO2
N/A N=285 Evaluation of the Wits Workout Wellness Program for Older Adults
Cognitive Decline · Social Isolation · Health Behaviors
Primary: Change in Cognitive Function — 0.28; .65; 1.84; -.73 T score
N/A N=73 Seniors Health and Activity Research Program-Pilot
Cognitive Function
Primary: Composite Cognitive Function in Z-scores (i.e. Which Converts Raw Data to Standard Deviation (SD) Units: [Score-mean]/SD]). This Composite is Formed by Averaging the…
Phase 4 N=34 Retinol on Human Skin Aging in East Asian Descent
Intrinsic Aging of Skin
Primary: Number of Genes Upregulated or Downregulated as Assessed by RNA Sequencing (Older Group, Retinol Versus Placebo) — 23; 21 genes
Phase 3 N=164 Calorie Restriction and Changes in Body Composition, Disease, Function, and Quality of Life in Older Adults
Obesity · Diabetes · Hypertension
Primary: Change in Abdominal Fat Mass — -192.6; -21.9; -275 Cubic cm
N/A N=48 Ageing and Acute Care Physicians' Performance
Ageing
Primary: CRM Performance During First Sim Scenario Assessed by Ottawa Global Rating Scale (GRS) — -0.299 Pearson correlation coefficient — p=0.039