N/A
N=13,182
Comorbidities and Outcomes in Early Rheumatoid Arthritis
Rheumatoid Arthritis
Bottom Line
View on ClinicalTrials.gov: NCT03675516 ↗Enrolled (actual)
13,182
Serious AEs
0.0%
Results posted
Mar 2022
Primary outcome: Primary: Event Rate for a Cardiovascular Composite of Incident Myocardial Infarction, Stroke, or Heart Failure — 10.62; 8.13 Events per 1000 person years
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- No specific intervention (Other)
- Age
- Pediatric, Adult, Older Adult · 10+ yrs
- Sex
- All
- Sponsor
- Momentum Data
- Primary completion
- Jan 2017
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Event Rate for a Cardiovascular Composite of Incident Myocardial Infarction, Stroke, or Heart Failure |
10.62; 8.13 | — |
| PRIMARY Event Rate for a Composite of Incident Infections. |
3506; 0 | — |
| SECONDARY Event Rate for Incident Stroke |
4.29; 3.82 | — |
| SECONDARY Event Rate for Incident Heart Failure |
3.98; 2.72 | — |
| SECONDARY Event Rate for a Joint Operations Composite, Comprised of Incident Joint Operations on Shoulder, Elbow, Wrist, Hand, Hip, Knee, Ankle and Foot |
20.11 | — |
Summary
Identify the burden of comorbidity at the time of diagnosis of rheumatoid arthritis. Identify the impact of comorbidity present at diagnosis on cardiovascular disease, death, rheumatoid arthritis disease progression and infections.
Eligibility Criteria
Inclusion Criteria
- Diagnosis of rheumatoid arthritis prior to 1st January 2017
- Aged ≥18 years old
Exclusion Criteria
- Patients with another other rheumatic disease
Data sourced from ClinicalTrials.gov (NCT03675516). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.