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Phase 4 Completed N=86 Randomized Single-blind Treatment

Clinical Comparison of Femoral Nerve Versus Adductor Canal Block Following Anterior Ligament Reconstruction

Source: ClinicalTrials.gov NCT03704376 ↗
Enrolled (actual)
86
Serious AEs
0.0%
Results posted
Dec 2018
Primary outcomePrimary: Quadriceps Muscle Activation as Assessed by Surface Electromyography (sEMG) — 266.5; 212.5 microvolts (uV)
◆ Published Evidence
Established
48citations · ~7 / year
Adductor Canal Nerve Versus Femoral Nerve Blockade for Pain Control and Quadriceps Function Following Anterior Cruciate Ligament Reconstruction With Patellar Tendon Autograft: A Prospective Randomized Trial.
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association · 2019 · Likely link

Summary

This study will examine the potential differences between femoral nerve blockade (FNB) and adductor canal blockade (ACB) for pain control and quadriceps muscle activation for patients following anterior cruciate ligament (ACL) reconstruction.

Linked Publications (5)

  • Adductor Canal Nerve Versus Femoral Nerve Blockade for Pain Control and Quadriceps Function Following Anterior Cruciate Ligament Reconstruction With Patellar Tendon Autograft: A Prospective Randomized Trial.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association · 2019 · 48 citations · Likely link
  • Platelet-Rich Plasma Augmentation of Meniscal Repair in the Setting of Anterior Cruciate Ligament Reconstruction.
    The American journal of sports medicine · 2021 · 28 citations · Likely link
  • Subsequent Surgery for Loss of Motion After Anterior Cruciate Ligament Reconstruction Does Not Influence Function at 2 Years: A Matched Case-Control Analysis.
    The American journal of sports medicine · 2019 · 25 citations · Likely link
  • Comparison of Psychological Readiness to Return to Sport After Primary Versus Revision Anterior Cruciate Ligament Reconstruction.
    Orthopaedic journal of sports medicine · 2023 · 24 citations · Open access · Likely link
  • Relationship Between Bone Bruise Volume and Patient Outcomes After ACL Reconstruction.
    Orthopaedic journal of sports medicine · 2023 · 3 citations · Open access · Likely link

Outcome Measures

OutcomeResultp-value
PRIMARY
Quadriceps Muscle Activation as Assessed by Surface Electromyography (sEMG)
266.5; 212.5
PRIMARY
Quadriceps Muscle Activation as Assessed by Surface Electromyography (EMG)
109.1; 94.1
SECONDARY
Number of Successful Repetitions With Straight Leg Raise Test
29.7; 30
SECONDARY
Postoperative Pain Control as Assessed by a Numeric Pain Rating Scale
SECONDARY
Narcotics Use as Assessed by Morphine Equivalents Consumed
14.8; 16.0

Eligibility Criteria

Inclusion Criteria

  • Males & Females ages 16-30 yrs
  • Undergoing ACL reconstruction by Co-Investigator (Walter Lowe)
  • Receiving peri-operative FNB or ACB

Exclusion Criteria

  • Not enrolled within the COFAKS study
  • Receiving intrathecal nerve blockade or no blockade
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03704376) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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