Phase 4 N=86 Randomized Single-blind Treatment

Clinical Comparison of Femoral Nerve Versus Adductor Canal Block Following Anterior Ligament Reconstruction

Anterior Cruciate Ligament Injury

Bottom Line

View on ClinicalTrials.gov: NCT03704376 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Dec 2018

Primary outcome: Primary: Quadriceps Muscle Activation as Assessed by Surface Electromyography (sEMG) — 266.5; 212.5 microvolts (uV)

Study Design & Population

Study type: Interventional
Phase: Phase 4
Interventions: 30 ml of 0.2% ropivacaine (Drug); 15 ml of 0.2% ropivacaine (Drug); 100 mcg clonidine (Drug); High-frequency linear ultrasound transducer (Device)
Age: Pediatric, Adult · 16+ yrs
Sex: All
Sponsor: The University of Texas Health Science Center, Houston
Primary completion: Nov 2017

Outcome Measures

Outcome	Result	p-value
PRIMARY Quadriceps Muscle Activation as Assessed by Surface Electromyography (sEMG)	266.5; 212.5	—
PRIMARY Quadriceps Muscle Activation as Assessed by Surface Electromyography (EMG)	109.1; 94.1	—
PRIMARY Quadriceps Muscle Activation as Assessed by Surface Electromyography (EMG)	109.1; 94.1	—
SECONDARY Number of Successful Repetitions With Straight Leg Raise Test	29.7; 30	—
SECONDARY Number of Successful Repetitions With Straight Leg Raise Test	29.7; 30	—
SECONDARY Number of Successful Repetitions With Straight Leg Raise Test	29.7; 30	—
SECONDARY Postoperative Pain Control as Assessed by a Numeric Pain Rating Scale	—	—
SECONDARY Postoperative Pain Control as Assessed by a Numeric Pain Rating Scale	—	—
SECONDARY Postoperative Pain Control as Assessed by a Numeric Pain Rating Scale	—	—
SECONDARY Postoperative Pain Control as Assessed by a Numeric Pain Rating Scale	—	—
SECONDARY Postoperative Pain Control as Assessed by a Numeric Pain Rating Scale	—	—
SECONDARY Postoperative Pain Control as Assessed by a Numeric Pain Rating Scale	—	—
SECONDARY Postoperative Pain Control as Assessed by a Numeric Pain Rating Scale	—	—
SECONDARY Postoperative Pain Control as Assessed by a Numeric Pain Rating Scale	—	—
SECONDARY Postoperative Pain Control as Assessed by a Numeric Pain Rating Scale	—	—
SECONDARY Postoperative Pain Control as Assessed by a Numeric Pain Rating Scale	—	—
SECONDARY Postoperative Pain Control as Assessed by a Numeric Pain Rating Scale	—	—
SECONDARY Postoperative Pain Control as Assessed by a Numeric Pain Rating Scale	—	—
SECONDARY Postoperative Pain Control as Assessed by a Numeric Pain Rating Scale	—	—
SECONDARY Narcotics Use as Assessed by Morphine Equivalents Consumed	14.8; 16.0	—

Summary

This study will examine the potential differences between femoral nerve blockade (FNB) and adductor canal blockade (ACB) for pain control and quadriceps muscle activation for patients following anterior cruciate ligament (ACL) reconstruction.

Eligibility Criteria

Inclusion Criteria

Males & Females ages 16-30 yrs
Undergoing ACL reconstruction by Co-Investigator (Walter Lowe)
Receiving peri-operative FNB or ACB

Exclusion Criteria

Not enrolled within the COFAKS study
Receiving intrathecal nerve blockade or no blockade

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03704376). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.