N/A
N=135
Flexible Intubation Scope With or Without Video Laryngoscope in Supporting Endotracheal Tube Placement in Patients With Head and Neck Cancer Before Surgery
Head and Neck Neoplasm
Bottom Line
View on ClinicalTrials.gov: NCT03757091 ↗Enrolled (actual)
135
Serious AEs
0.0%
Results posted
Jan 2026
Primary outcome: Primary: Difficult Endotracheal Tube (ETT) Placement — 40; 29; 27; 34 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Laryngoscopy (Device); Tracheal Intubation (Procedure)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- M.D. Anderson Cancer Center
- Primary completion
- Nov 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Difficult Endotracheal Tube (ETT) Placement |
40; 29; 27; 34 | — |
| SECONDARY Intubation Time |
58.37; 50.92 | — |
| SECONDARY Number of Intubation Attempts |
50; 54; 14; 4 | — |
| SECONDARY Rate of Failure at Intubation |
7.81; 1.72 | — |
| SECONDARY Ease of Intubation (Provider Assessment) |
31; 40; 14; 14; 9; 6 | — |
Summary
This trial studies how well flexible intubation scope with or without video laryngoscope works in supporting endotracheal tube placement in patients with head and neck cancer before surgery. Flexible intubation scope and video laryngoscope are devices that have a small camera to help the doctor see the patient's airway on a screen. Both devices may help the doctor who gives anesthesia prevent complications from placing the breathing tube (such as pain or mouth injury).
Eligibility Criteria
Inclusion Criteria
- Ages ≥ 18 years of age
- All surgical patients with known or suspected difficult airways that meet at least three (3) of the Difficult Airway criteria [Mallampati III-IV, Neck circumference > 40 cm, Sternomental distance < 12 cm, Thyromental distance < 6 cm, Mouth opening < 4 cm, BMI ≥ 35 kg/m2, Upper Lip Bite Test - ULBT (class III)] or history of radiation to the head and neck area or oral pathology obstructing the glottic view
- American Society of Anesthesiology (ASA) I-IV
- Has provided written informed consent
Exclusion Criteria
- Active bleeding from nasopharynx or oropharynx
- Trismus
- Oral pathology obstructing the glottic view
- Planned awake or nasal intubation
- Neuromuscular Blockade (NMB) contraindicated post-induction
- Emergency endotracheal intubation and patients intubated pre and post-surgery
- Surgical procedures such as Tracheostomy, Laryngectomy, Esophagectomy
- Patient refusal or inability to consent for study participation
- American Society of Anesthesiology (ASA) V
- Pregnant females
Data sourced from ClinicalTrials.gov (NCT03757091). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.