N/A
N=171
Acupressure for Fatigue in Ovarian Cancer Survivors
Fatigue · Ovarian Cancer
Bottom Line
View on ClinicalTrials.gov: NCT03763838 ↗Enrolled (actual)
171
Serious AEs
0.6%
Results posted
Feb 2026
Primary outcome: Primary: Change in Level of Fatigue at Week 6 — 5.57; 5.30; 5.38; 3.52 mean score
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Acupressure (Other); Sham acupressure (Other); Standard of Care (Other)
- Age
- Adult, Older Adult · 21+ yrs
- Sex
- Female
- Sponsor
- University of Michigan Rogel Cancer Center
- Primary completion
- Jun 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Level of Fatigue at Week 6 |
5.57; 5.30; 5.38; 3.52; 4.06; 4.96 | — |
| PRIMARY Change in Level of Fatigue up to Week 24 |
5.57; 5.30; 5.38; 3.55; 4.09; 5.15 | — |
| SECONDARY Change in Quality of Life at Week 6 |
9.32; 9.73; 8.59; 8.26; 9.31; 8.67 | — |
| SECONDARY Change in Quality of Life up to Week 24 |
9.32; 9.73; 8.59; 8.06; 8.58; 8.16 | — |
| SECONDARY Change in Sleep Quality at Week 6 |
9.32; 9.73; 8.59; 8.26; 9.31; 8.67 | — |
| SECONDARY Change in Sleep Quality up to Week 24 |
9.32; 9.73; 8.59; 8.06; 8.58; 8.16 | — |
Summary
The purpose of this study is to see if accupressure can help reduce the severity of fatigue experienced by ovarian cancer patients. Acupressure involves applying mild to moderate physical pressure by fingers, hand or a device to specific points on the skin to try to bring about a change in the body's functioning, in this case relief from chronic fatigue.
Eligibility Criteria
Inclusion Criteria
- Women aged 21 and older
- Diagnosis of ovarian cancer, stages I to IV
- Have average persistent fatigue defined a >=4 on the Brief Fatigue Inventory.
- Fatigue must have started at or after the diagnosis of ovarian cancer
- Completed all primary cancer treatments (surgery, chemotherapy at least 6 months prior), except maintenance therapies
- No other planned interventions for fatigue other than current stable medication
Exclusion Criteria
- Medically unstable
- Acupuncture or acupressure receipt in past year
- Have a diagnosis of untreated mood disorder, e.g., bipolar or major depressive disorder
- Have a current diagnosis of anemia
- Have a current untreated diagnosis of hypothyroidism
- Have an initiation, a cessation or change of treatment of any chronic medications, dietary supplements, behavioral therapy, physical therapy, etc., or any planned change of medications, supplements or therapies during the study
- Have the possibility of becoming pregnant
Data sourced from ClinicalTrials.gov (NCT03763838). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.