Phase 3
Completed N=18
Folinic Acid in Autism
Source: ClinicalTrials.gov NCT03771560 ↗Enrolled (actual)
18
Serious AEs
0.0%
Results posted
Dec 2019
Primary outcomePrimary: Aberrant Behavior Checklist (ABC) - Parent Reported Change — -2.4 score on a scale — p=0.56
◆ Published Evidence
No publication linked
No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.
Summary
An examination of changes in urinary metabolites with use of folinic acid in children with autism spectrum disorder (ASD). Investigators will also measure behavioral measures and academic measures monthly at school with teachers and parents report.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Aberrant Behavior Checklist (ABC) - Parent Reported Change |
-2.4 | 0.56 |
| PRIMARY Aberrant Behavior Checklist (ABC) - Teacher Reported Change |
1.2 | 0.68 |
| SECONDARY Social Responsiveness Scale (SRS) - Parent Reported Change |
-7.8 | 0.095 |
| SECONDARY Social Responsiveness Scale (SRS) - Teacher Reported Change |
-0.5 | 0.95 |
| SECONDARY Pediatric Quality of Life (PedsQL) - Parent Reported Change |
-0.8 | 0.69 |
Eligibility Criteria
Inclusion Criteria
- Between ages 5 and 25
Exclusion Criteria
- Not currently taking folinic acid
Data sourced from ClinicalTrials.gov (NCT03771560). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.