N/A
Completed N=151
Rhythm Experience and Africana Culture Trial
Cognitive Performance · Brain Structure
Source: ClinicalTrials.gov NCT03771716 ↗
Enrolled (actual)
151
Serious AEs
6.0%
Results posted
Aug 2025
Primary outcomePrimary: Flanker Performance — -0.1055; -0.0586 score on a scale
Summary
REACT is a randomized intervention to examine the benefits of African Dance as a method to increase physical activity behaviors in older adults. In this 6- month intervention, older African Americans will be randomly assigned to either an African Dance or an Africana Culture class. Both before and at the completion of the intervention, the investigators will collect a comprehensive neuropsychological battery and MRI scans of brain health and function to better study how physical activity influences neurocognitive health in African Americans.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Flanker Performance |
-0.1055; -0.0586 | — |
| SECONDARY Hippocampal Volume (mm3) |
-7.57; -59.71 | — |
Eligibility Criteria
Inclusion Criteria
- self identifies race as African American
- between 60 and 80 years of age
- ambulatory without pain or the assistance of walking devices
- no history of falls or balance problems
- able to speak and read English
- available during the times classes are offered and able to make at least 80% of classes (e.g., no long-term travel plans)
- reliable means of transportation
- scores above the range on the Brief Telephone Interview for Cognitive Status (TICS) indicative of moderate to severe cognitive impairment (scores 21 or above)
- no diagnosis of a neurological disease or psychiatric conditions
- eligible to undergo MRI (not claustrophobic and no metal or history of injury involving metal).
- Fully vaccinated for coronavirus disease (COVID-19).
Exclusion Criteria
- self identifies race as other than African American
- not between 60 and 80 years of age
- not ambulatory without pain or the assistance of walking devices
- history of falls or balance problems
- unable to speak and read English
- unavailable during the times classes are offered or unable to make at least 80% of classes (e.g., indicates long-term travel plans during intervention period)
- no reliable means of transportation
- scores in range on the TICS indicative of moderate to severe cognitive impairment (scores 21 or below)
- has a diagnosis of a neurological disease or psychiatric condition
- ineligible to undergo MRI (claustrophobic and/or metal in body or history of injury involving metal).
Data sourced from ClinicalTrials.gov (NCT03771716). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.