Clinical Trial Search

Primary: Working Memory — 0.86; 0.04 digits recalled

Primary: Number of Incorrect Trials During the Computer-administered Attention-Switching Task Test.Attention-Switching Task Latency Error Rate — 5.11; 3.1 trials

Primary: Cerebral Metabolic Rate of Oxygen (CMRO2) — 8.17 micro-mol/100g/min

Primary: UCSD Performance-based Skills Assessment Total Score (Measures Functional Capacity) — 82.7; 84.4 units on a scale

Primary: Percentage of Trials Correct On Working Memory Test — 87.69; 91.57; 88.01; 91.68 percentage of correct trials — p=>0.05

Primary: Change in Working Memory — 51.33; 43.15 mean T score on working memory tests — p=.013

Primary: Auditory Memory Attention Index — 89.0; 94.3 standard score units — p=<0.01

Primary: Proportion of Correct Targets Identified Minus False Identifications in the n-Back Task — .80; .70; .68; .21 score on a scale

Primary: Changes in the Breakfast Game Performance: Number of Tables Set Score — 1.61; 1.43 score on a scale (change)

Primary: Change in Mean Computer-based Cognitive Assessment (CogState) Composite Score at Week 4 — -0.10; -0.07 Score on a scale — p=0.231

Primary: Change in NIH Sponsored Executive Abilities: Measures and Instruments for Neurobehavioral Evaluation and Research (NIH-EXAMINER) Executive Composite Score — 0.34; -.42…

Primary: Completion of Academic Semesters — 1.95; 1.67; 1.89; 1.67 Courses completed — p=0.029

Primary: Symbol Digit Modalities Test — 41.18; 35.06; 45.05; 38.63 score on a scale

Primary: California Verbal Learning Test-II (CLVT-II) — 55.84; 55.39 age adjusted t-scores

Primary: Change From Baseline in COWA Unique Word Count — -0.407725385; -0.425898667; -0.412534118; -0.108298333 Word Count

Primary: Cognitive Screening Results (Montreal Cognitive Assessment) — 28.69; 22.37; 23.375; 23 score on a scale

Primary: Scores Digital (ISC) Tests — 41.3; 17.9; 19.3; 29.1 units on a scale — p=>.05

Primary: Composite Score of Attention and Executive Functioning From a Neurocognitive Test Battery — 0.18; -0.06 units on a scale

Primary: Change in Quality of Life in Neurological Disorders Cognitive Function Version 2 (Neuro-QoL CF v2) T-scores at 6 Weeks — 49.9; 49.1; 50; 45.9 T-score — p=0.015

Primary: Button Press Reaction Time — 1.86; 1.53; 1.29 Seconds — p=<.001

Primary: Neuropsychological Performance in Neuropsychological Test: Verbal Learning Memory Test (VLMT) — 57.2; 57.2 score on a scale — p=0.74

Primary: Change Scores in Timed up and go With Cognitive Task — -0.89; -0.37; -0.64; -1.42 seconds — p=0.562

Primary: FCI Score at Follow-up — 147.3; 164.0; 123.3; 150.8 points awarded for correct items

Primary: New Occurrence in Dementia Care-A Composite Endpoint Including New Cognitive Diagnoses, Laboratory Investigations Related to Cognitive Impairment, New Dementia…

Primary: Accuracy on the Tower of London Task — 81.2; 82.3; 88.1; 84.0 percentage of correct responses

Primary: Change in the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) — -0.89; 0.55 score

Primary: Task Completion Rate — 66; 57 Percentage of eligible participants

Primary: Change in Magnetoencephalography (MEG) Connectivity Measures

Primary: Number of Remembered Items — 1.72; 1.68; 1.68; 1.65 remembered items — p=0.783

Primary: Cognitive Performance — 76.7; 75.5; 67.2; 77.1 percentage correct of all trials