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N/A N=541

Brain and Genetic Predictors of Individual Differences in Pain and Analgesia

Pain, Acute

Enrolled (actual)
541
Serious AEs
0.0%
Results posted
May 2025
Primary outcome: Primary: Pain Rating Scores Made on a Visual Analog Scale (VAS) — 0.136; 0.190; 0.126; 0.160 Score on a scale — p=<0.001

Study Design & Population

Study type
Observational
Phase
N/A
Interventions
Placebo Cream (Behavioral); Control Cream (Behavioral)
Age
Adult · 18+ yrs
Sex
All
Sponsor
Trustees of Dartmouth College
Primary completion
Oct 2023

Outcome Measures

OutcomeResultp-value
PRIMARY
Pain Rating Scores Made on a Visual Analog Scale (VAS)
0.136; 0.190; 0.126; 0.160 <0.001 sig

Summary

The purpose of the study is to gain a better understanding of pain processing in the brain. Our understanding of how pain is processed in the brain is limited. We are testing for individual differences in pain perception and emotion.

Eligibility Criteria

Inclusion Criteria

  • Participants must be registered in the Colorado Community Twin Sample (CTS).

Exclusion Criteria

  • Not being registered in the Colorado Community Twin Sample (CTS).
  • Any MRI contraindications.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03781570). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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