N/A
N=43
VR-based Rehabilitation in the Treatment and Prevention of Sarcopenia of Older Residents
Sarcopenia
Bottom Line
View on ClinicalTrials.gov: NCT03809104 ↗Enrolled (actual)
43
Serious AEs
0.0%
Results posted
Jan 2020
Primary outcome: Primary: Change of Hand-grip Strength of the Dominant Hand Between the Third Month and the Baseline — 5.02 kg
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Virtual reality-based rehabilitation programs (Other)
- Age
- Adult, Older Adult · 60+ yrs
- Sex
- All
- Sponsor
- Cishan Hospital, Ministry of Health and Welfare
- Primary completion
- Sep 2019
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change of Hand-grip Strength of the Dominant Hand Between the Third Month and the Baseline |
5.02 | — |
| PRIMARY Change of Walking Speed Between the Third Month and the Baseline |
0.2 | — |
| PRIMARY Change of Appendicular Skeletal Muscle Mass Between the Third Month and the Baseline |
0.21 | — |
| SECONDARY Range of Motions in Dominant Upper Extremity |
130.36; 139.07; 143.07; 149.79; 71.68; 75.50 | — |
| SECONDARY Strength of Biceps Brachii and Triceps Brachii of the Dominant Upper Extremity |
5.03; 5.48; 5.80; 6.44; 5.06; 5.55 | — |
| SECONDARY Box and Block Test |
26.86; 34.14; 36.04; 37.57 | — |
Summary
Background:
Sarcopenia is the progressive loss of skeletal muscle mass and decline of muscle function associated with aging. The prevalence of sarcopenia among people older than 65 years old in Taiwan is over 20%. Sarcopenia is one of the most important causes of functional decline and loss of independence, even mortality in older adults. Literatures have found that resistant or aerobic exercise could improve muscle strength and function in older adults. However, due to shortage in healthcare provider, long-term rehabilitation program is difficult to provide in senior caring facilities of countryside in Taiwan.
Method:
The investigators conducted a study to screen sarcopenia among residents in senior caring facilities in Ci-Shan and Mei-Nong district, Kaohsiung, Taiwan. Older adults diagnosed as sarcopenia after screening received a virtual reality (VR)-based rehabilitation program that lasts for 12 weeks, twice per week, 30 minutes per time. The program was combined with progressive resistant training and functional movement of dominant upper (UE) limb. Criteria of sarcopenia including (1) handgrip strength of dominant hand (HGS), (2) walking speed, and (3) skeletal muscle mass of 4 extremities (SKM), were measured as primary outcomes. (1) Range of motions in dominant UE (ROM), (2) maximal voluntary isometric contraction of biceps/triceps brachial muscles of dominant side (MVC of biceps/triceps), and (3) box and block test (BBT), were measured as secondary outcomes before and after the programs.
Anticipated benefits:
VR-based rehabilitation program could enhance the motivation toward rehabilitation of older adults and reduce the health provider demand of senior caring facilities in countryside. It could also increase muscle mass, strength, and functional ability of dominant UE and reach the clinical effectiveness in treatment of sarcopenia.
Eligibility Criteria
Inclusion Criteria
- All the rehabilitation subjects are selected from the nursing home and day care center of Chi-Shan Hospital and over 60 years of age.
- Participants meet the diagnostic criteria of sarcopenia based on the The Asian Working Group of Sarcopenia:
(1) Muscle mass lower than norm for two standard deviations and (2) Grip strength: men lower than 26 kg and women lower than 18 kg (measured by handgrip denominator used in physical examination) or an average gait speed lower than 0.8m/ sec.
- Cognitive functions and physical strength are capable of completing the rehabilitation program which lasts for 30 minutes
Exclusion Criteria
- The ones who have uncontrollable high blood pressure, are recently infected, have major cardiovascular diseases and are prohibited to participate in sports exercise by the American College of Sports Medicine are excluded from the selection.
- The ones who are bedridden are excluded from the selection.
Data sourced from ClinicalTrials.gov (NCT03809104). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.