N/A
N=416
Reducing Disparities in Living Donor Transplant Among African Americans
Kidney Transplant
Bottom Line
View on ClinicalTrials.gov: NCT03819686 ↗Enrolled (actual)
416
Serious AEs
0.0%
Results posted
Mar 2025
Primary outcome: Primary: Percent of Patients With at Least One Inquiry From a Potential Living Donor — 15.63; 15.63; 15.77; 15.87 percentage of participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Living ACTS website (Behavioral); Standard transplant education procedures (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Emory University
- Primary completion
- Jan 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Percent of Patients With at Least One Inquiry From a Potential Living Donor |
15.63; 15.63; 15.77; 15.87 | — |
| SECONDARY Knowledge and Understanding of Donation/Transplantation Assessment Score |
10.00; 10.18; 10.14; 10.03 | — |
| SECONDARY Motivation Scale Score to Ask a Family Member to be a Living Donor |
36.03; 35.58; 37.00; 36.38 | — |
| SECONDARY Confidence in Initiating a Conversation About LDKT |
40.38; 39.45; 41.98; 40.46 | — |
Summary
For most of the patients in the United States with end stage renal disease (ESRD), kidney transplantation represents the optimal treatment, and living donor kidney transplantation (LDKT) is preferable. Nevertheless, there are pervasive racial disparities in access to LDKT. The main outcome of this study is change in the proportion of study participants who have at least one living donor inquiry by friends/family over study period.The long-term objective is to understand the combined effect of a systems-level intervention (Transplant Referral EXchange or T-REX) and a culturally-sensitive individual-level educational intervention (web-based Living ACTS: About Choices in Transplantation and Sharing) on racial disparities in access to LDKT.
Eligibility Criteria
Inclusion Criteria
- All patients referred (from dialysis facility, chronic kidney disease clinic, or self) and scheduled for an evaluation at one of the four study sites within the study time period.
- African American or Black
- age 18 to 70 years
- BMI < 39
- English-speaking
Data sourced from ClinicalTrials.gov (NCT03819686). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.