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N/A Completed N=148,166

Trends in the Epidemiology and Treatment of Atopic Dermatitis in the United Kingdom (UK)

Atopic Dermatitis Eczema · Atopic Dermatitis
Source: ClinicalTrials.gov NCT03823794 ↗
Enrolled (actual)
148,166
Serious AEs
—
Results posted
Jun 2025
Primary outcomePrimary: Prescription Rates for Atopic Dermatitis Related Treatments: Emollients and Soap Substitutes — 76095 Participants

Summary

Atopic dermatitis (AD), commonly called eczema, is one of the most frequently occurring skin conditions. It is estimated to affect around one fifth of children in developed countries and is also becoming increasingly common in less developed countries. Exact estimates of how common eczema is, vary considerably and there has not been an in-depth analysis of the number of people with eczema in the UK. It is also unclear which groups of people are most affected and which treatment options are being used. Most people with eczema are managed by their general practitioner (GP) with only a few people requiring specialist care. GP records therefore provide an excellent opportunity to explore how common eczema is and which treatments are being used currently.

Outcome Measures

OutcomeResultp-value
PRIMARY
Prescription Rates for Atopic Dermatitis Related Treatments: Emollients and Soap Substitutes
76095 —
PRIMARY
Prescription Rates for Atopic Dermatitis Related Treatments: Mild Topical Corticosteroids (TCS)
40478 —
PRIMARY
Prescription Rates for Atopic Dermatitis Related Treatments: Moderate Topical Corticosteroids (TCS)
19575 —
PRIMARY
Prescription Rates for Atopic Dermatitis Related Treatments: Potent Topical Corticosteroids (TCS)
34997 —
PRIMARY
Prescription Rates for Atopic Dermatitis Related Treatments: Very Potent Topical Corticosteroids (TCS)
6478 —
PRIMARY
Prescription Rates for Atopic Dermatitis Related Treatments: Topical Calcineurin Inhibitors (TCI)
2683 —
PRIMARY
Prescription Rates for Atopic Dermatitis Related Treatments: Topical Antimicrobials
19378 —
PRIMARY
Prescription Rates for Atopic Dermatitis Related Treatments: Antihistamin
29041 —
PRIMARY
Prescription Rates for Atopic Dermatitis Related Treatments: Systemic Immuno-modulatory Therapy
2785 —
PRIMARY
Prescription Rates for Atopic Dermatitis Related Treatments: Oral Corticosteroids
12087 —
PRIMARY
Specialist Referrals
5.0 —
PRIMARY
Primary Care Referrals
112.0 —

Eligibility Criteria

Inclusion Criteria

  • All paediatric and adult patients registered with an Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC) contributing GP practice during the study period (2008-2018) and with at least one year of follow-up.

Exclusion Criteria

  • The presence of psoriasis, photodermatitis, or ichthyosis
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03823794). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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