N/A
N=147
Impacts of Aquatic vs Land Walking on Vascular Health and Exercise Tolerance in Patients With Peripheral Artery Disease
Peripheral Artery Disease · Vascular Function · Exercise Tolerance · Peripheral Arterial Disease
Bottom Line
View on ClinicalTrials.gov: NCT03849300 ↗Enrolled (actual)
147
Serious AEs
0.0%
Results posted
Mar 2020
Primary outcome: Primary: Peripheral Arterial Stiffness — 12.3; 10.2; 12.4; 12.8 meters per second
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Aquatic walking exercise program group 1 (Other); Aquatic walking exercise program group 2 (Other); Land-based walking exercise group (Other)
- Age
- Adult, Older Adult · 50+ yrs
- Sex
- All
- Sponsor
- Pusan National University
- Primary completion
- Aug 2017
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Peripheral Arterial Stiffness |
12.3; 10.2; 12.4; 12.8 | — |
| SECONDARY Body Composition |
30.5; 28.5; 28.5; 28.7 | — |
| SECONDARY Resting Heart Rate |
70.2; 67.9; 71; 71 | — |
| SECONDARY Systolic Blood Pressure |
132.4; 130.4; 126; 129 | — |
| SECONDARY Resting Metabolic Rate |
1022.9; 1021.5; 1282; 1272 | — |
| SECONDARY Cardiorespiratory Capacity |
17.8; 20.5 | — |
| SECONDARY Exercise Tolerance - Walking Capacity |
358; 440; 438; 404 | — |
| SECONDARY Upper Body Strength |
25.1; 26; 26; 27 | — |
| SECONDARY Lower Body Strength |
45.2; 47.3; 48; 46 | — |
| SECONDARY Lower Body Flexibility |
15.2; 15.9 | — |
| SECONDARY Medical Outcomes Study Short-Form 36 General Health Survey for Physical Function |
46; 52; 55; 53 | — |
| SECONDARY Diastolic Blood Pressure |
90.7; 82.7; 84; 85 | — |
| SECONDARY Systemic Arterial Stiffness |
14.7; 14.8 | — |
| SECONDARY Time to Onset of Claudication |
252; 213 | — |
Summary
The purpose of this study was to examine the impacts of a 12-week aquatic walking exercise program on body composition, vascular function, cardiorespiratory capacity, exercise tolerance, muscular strength, and physical function in patients with peripheral artery disease (PAD). The effects of the 12-week aquatic walking exercise program were also compared to the effects of a 12-week land-based walking exercise program.
Eligibility Criteria
Inclusion Criteria
- Peripheral artery disease (ankle-brachial index between 0.6 and 0.9)
- 50-85 years of age
- Sedentary (less than 1 hour of regular exercise participation per week within the previous year)
Exclusion Criteria
- current smoker (smoking within previous 6 months)
- psychiatric conditions
- pulmonary disease
- renal disease
- thyroid disease
Data sourced from ClinicalTrials.gov (NCT03849300). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.