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N/A N=34 Randomized Single-blind Supportive Care

Tailored Home-Based Exercise Program for Multiple Chronic Conditions

Cancer · Hypertension · Diabetes

Enrolled (actual)
34
Serious AEs
0.0%
Results posted
Sep 2022
Primary outcome: Primary: Change in Fatigue as Assessed by Patient-Reported Outcomes Measurement Information System (PROMIS) Short Form v1.0-Fatigue 6a — -1.61; 4.26 T-score

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Tailored Technology-Enhance Home-based exercise program (iHBE) (Other)
Age
Adult, Older Adult · 21+ yrs
Sex
All
Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Primary completion
Jan 2021

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in Fatigue as Assessed by Patient-Reported Outcomes Measurement Information System (PROMIS) Short Form v1.0-Fatigue 6a
-1.61; 4.26
PRIMARY
Change in Resilience as Assessed by Connor-Davidson Resilience Scale
0.00; 0.89
PRIMARY
Change in Physical Well Being
14.48; -2.83
PRIMARY
Change in Mental Well Being
2.51; 0.16
SECONDARY
Physical Activity
1279.11; 805.46
SECONDARY
Change in Brain-Derived Neurotrophic Factor Level (in Serum)
SECONDARY
Change in Brain-Derived Neurotrophic Factor Level (in Sweat)

Summary

A home-based, tailored, technology-enhanced home-based exercise program (iHBE) using a combination of the integrated mobile technologies (wearable device and phone application) and tailored home-based exercise will be pilot tested. Participants will choose one of the four home-based exercise options [National Institute of Aging (NIA) Go4Life (an exercise and physical activity campaign from the NIA), Iyengar-style yoga, walking, and modified Otago exercise] based on participants' preference and goals. The integrated mobile technologies system will allow the investigators to extract heart rate data directly from the wearable device to the research server. This data will be used to provide appropriate and personalized feedback on physical performance. The survey and notification to the participants on the smartphone.

Eligibility Criteria

Inclusion Criteria

  • participants diagnosed with solid tumor cancer who have completed cancer treatment at least 6 months;
  • diagnosed with diabetes and/or hypertension for at least a year;
  • aged 21 years or older,
  • have an annual household incomes of below $50,000 for families of three,
  • the average fatigue level within the past 7 days at the level of 3 or more on the 0 (no fatigue) to 10 (worse fatigue) Likert scale
  • give informed consent.

Exclusion Criteria

  • currently undergoing treatment for cancer;
  • have an active infection (e.g., fever, localized redness, swelling, sinus congestion);
  • diagnosed with a psychological disorder (e.g., suicidal or homicidal tendencies, extreme anxiety or depression)
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03874754). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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