N/A
Completed N=142
Umbilical Cord Clamping: What Are the Benefits
Delayed Cord Clamping
Source: ClinicalTrials.gov NCT03878602 ↗
Enrolled (actual)
142
Serious AEs
0.0%
Results posted
Apr 2021
Primary outcomePrimary: Change of Heart Rate After Delayed Umbilical Clamping — 164; 157; 163; 155 bpm
Summary
Umbilical cord clumping consists in the binding of the umbilical cord by nipper to interrupt blood flow from placenta to foetus. Umbilical cord can be clamped within 30s or at least 1 min after birth. A lot of studies have shown that delayed umbilical cord clamping is associated with greater haemoglobin concentration, better iron storage between 3-6 months of life and lower incidence for transfusion and neonatal hypotension compared to immediate umbilical cord clumping. Newborns subjected to Caesarean Section showed greater value of haemoglobin and lower value of red blood cells compared to newborns birth by vaginal delivery. Despite evidence of beneficial effects for delayed umbilical cord clamping after eutocic delivery, this practice is not yet taken into consideration after elective Caesarean Section.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change of Heart Rate After Delayed Umbilical Clamping |
164; 157; 163; 155 | — |
| PRIMARY Change of Saturation After Delayed Umbilical Clamping |
88.98; 89.169; 95.238; 96.046 | — |
| PRIMARY Change of Temperature After Delayed Umbilical Clamping |
36.60; 36.64 | — |
| SECONDARY Misuration of the Hemo Gluco Test After Delayed Umbilical Clamping |
60.32; 56.02 | — |
| SECONDARY Misuration of the Hematocrit After Delayed Umbilical Clamping |
51.56; 56.71 | — |
| SECONDARY Misuration of the Bilirubin After Delayed Umbilical Clamping |
7.06; 8.54 | — |
Eligibility Criteria
Inclusion Criteria
- Birth Body Weight = appropriate for gestational age
- Delivery mode= Elective Caesarean Section
- Mothers' BMI = 19-24,9
- Mothers'age ≤ 37 years
Exclusion Criteria
- Admission in NICU;
- Neonatal Resuscitation
- Hypoxic-ischemic events: detachment of placenta, prolapse of the funiculus, uterine rupture, shoulder dystocia, premature rupture of foetal membranes, placenta previa, maternal collapse, embolism amniotic, maternal cardiac arrest
- Pathologies ;
- Smoking mothers;
- Assumption of drugs during pregnancy
- Mother toxicomaniac
Data sourced from ClinicalTrials.gov (NCT03878602). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.