N/A
N=71
AllyQuest Adherence App Intervention for HIV-positive Men Who Have Sex With Men and Transgender Women: Pilot Trial
Hiv · HIV/AIDS · Medication Adherence · Sexual Behavior · Sexually Transmitted Infections (Not HIV or Hepatitis)
Bottom Line
View on ClinicalTrials.gov: NCT03916484 ↗Enrolled (actual)
71
Serious AEs
0.0%
Results posted
May 2023
Primary outcome: Primary: Intervention Feasibility: Average Proportion of Days of Any App Use — 0.64; 0.40; 0.27; 0.64 proportion of days
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- AllyQuest HIV Medication Adherence app-delivered intervention (Behavioral); AllyQuest HIV Medication Adherence app-delivered intervention + NSC (Behavioral)
- Age
- Pediatric, Adult · 15+ yrs
- Sex
- Male
- Sponsor
- University of North Carolina, Chapel Hill
- Primary completion
- Jun 2022
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Intervention Feasibility: Average Proportion of Days of Any App Use |
0.64; 0.40; 0.27; 0.64; 0.42 | — |
| PRIMARY Intervention Feasibility: Average Proportion of Days of HIV Medication Tracked |
0.80; 0.50; 0.38; 0.81; 0.54 | — |
| PRIMARY Intervention Acceptability: Mean Intervention Acceptability CSQ-8 Score |
— | — |
| PRIMARY Intervention Acceptability: Mean Intervention Acceptability Score |
20.95; 19.97; 18.36; 17.06; 19.48 | — |
| SECONDARY Mean Percent of Past 30-Day ART Medication Adherence |
99.00; 88.15; 97.09; 84.42; 91.09 | 0.33 |
| SECONDARY Mean Percent ART Medication Adherence Over Time |
98.75; 80.77; 73.00; 98.42; 84.69; 98.75 | 1.00 |
| SECONDARY Number of Participants With Viral Suppression |
3; 19; 8; 3; 33 | 0.45 |
| SECONDARY Percent of Participants With Viral Suppression Over Time |
0.00; 28.00; 45.45; 71.43; 35.42; 60.00 | 0.25 |
| SECONDARY Percent of Participants With Viral Suppression Over Time |
0.00; 28.00; 45.45; 71.43; 35.42; 60.00 | 0.25 |
Summary
AllyQuest (AQ) is a theory-informed smart phone application that supports HIV medication adherence for young men who have sex with men and young transgender women who have sex with men (YMSM/YTW) via behavior change, social support, and game-based mechanics. This study aims to evaluate the feasibility and acceptability of AQ and AQ plus medication adherence counseling in a Sequential Multiple Assignment Randomization Trial.
Eligibility Criteria
Inclusion Criteria
- Living with HIV
- Assigned male at birth
- currently identify as male or transgender woman
- anal sex with another male or transgender woman(lifetime)
- access to a smart phone with data plan
- English literacy
- prescribed ART
- At least one of the following: Having failed to show up for or missed 1 or more scheduled HIV care appointment in the past 12 months OR Last HIV care visit was more than 6 months ago OR Self-reporting less than 90% ART adherence in the past 4 weeks OR have a detectable viral load measure in the past 12 months OR recently diagnosed with HIV (past 3 months)
Exclusion Criteria
- younger than 15, or older than 29
- assigned female at birth
- HIV negative or status unknown
Data sourced from ClinicalTrials.gov (NCT03916484). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.