N/A
Completed N=60
A Text-Based Adherence Game for Young People Living With HIV in Ghana
HIV · Medication Adherence
Source: ClinicalTrials.gov NCT03928717 ↗
Enrolled (actual)
60
Serious AEs
0.0%
Results posted
Jun 2024
Primary outcomePrimary: HIV-1 Viral Load (log10 Transformed) — 2.22; 2.18 log10 HIV copies/mL — p=<0.05
Summary
This study will develop and evaluate a game-based, text message intervention to promote adherence to HIV care among young people living with HIV (YPLH) in Ghana. Intervention development will be guided by feedback from YPLH, their treatment supporters, and clinic staff, consultation with a mobile health services team, and Social Action Theory. Patient participants will be recruited from an urban HIV clinic in Accra, Ghana to complete a randomized pilot of the intervention. All participants will receive a brief adherence counseling session and complete three assessments over the course of 12 months following enrollment. During this time, intervention participants will receive text messages and phone calls from a semi-automated text message system, clinic staff, and other individuals in their life (e.g., family, friends, and partners) who they have identified as supportive of their treatment. The study will provide a wealth of knowledge about YPLH in Ghana, a group vulnerable to poor treatment outcomes, and provide preliminary data on a novel adherence promotion intervention.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY HIV-1 Viral Load (log10 Transformed) |
2.22; 2.18 | <0.05 sig |
| PRIMARY Self-reported Medication Adherence |
80.73; 84.03 | <0.05 sig |
Eligibility Criteria
Inclusion Criteria
- Living with HIV
- Reads English and speaks English or a local language (e.g., Twi)
- On antiretroviral therapy
- Access to mobile phone throughout study period
- Able to give consent and not impaired by cognitive or medical limitations as per clinical assessment
- Not involved with another HIV prevention or adherence study
- Evidence of a detectable viral load
Exclusion Criteria
- None
Data sourced from ClinicalTrials.gov (NCT03928717). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.