N/A
Completed N=212
Guidance of Ultrasound in Intensive Care to Direct Euvolemia
Source: ClinicalTrials.gov NCT03938038 ↗Enrolled (actual)
212
Serious AEs
9.3%
Results posted
Apr 2024
Primary outcomePrimary: Number of Acute Kidney Injury (AKI)-Free Days — 1; 1 Days
Summary
The purpose of this study is to assess the effectiveness of routine ultrasound assessments of volume status and fluid responsiveness for goal-directed therapy (GDT)-based fluid resuscitation in reducing acute kidney injury (AKI) incidence and duration in trauma patients in a teaching institution.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Acute Kidney Injury (AKI)-Free Days |
1; 1 | — |
| PRIMARY Number of Participants Who Receive 3 or More Ultrasound Volume Assessments |
7; 0 | — |
| SECONDARY Number of Participants With Acute Kidney Injury (AKI) |
115; 119 | — |
| SECONDARY Stage of Acute Kidney Injury (AKI) |
67; 64; 32; 37; 16; 18 | — |
| SECONDARY Number of Participants With Need for Renal Replacement Therapy |
16; 18 | — |
| SECONDARY Quantity of Fluids Administered |
1215; 572 | — |
| SECONDARY Type of Fluids Administered |
— | — |
| SECONDARY Quantity of Diuretics Administered |
0; 0 | — |
| SECONDARY Time to Lactate Normalization |
— | — |
| SECONDARY Time to Creatinine Concentration <1.5 mg/dL or to Prehospital Baseline |
— | — |
| SECONDARY Time to Base Excess Normalization |
— | — |
| SECONDARY Number of Ventilator-free Days |
29; 29 | — |
| SECONDARY Number of ICU-free Days |
26; 26 | — |
Eligibility Criteria
Inclusion Criteria
- Injured patients that are admitted to the trauma ICU
Exclusion Criteria
- Incarceration
- Pregnancy
Data sourced from ClinicalTrials.gov (NCT03938038). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.