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N/A N=199 Randomized Basic Science

Perceptions of Cigarette Smoking in Young Adults

Smoking, Cigarette

Enrolled (actual)
199
Serious AEs
0.0%
Results posted
Dec 2024
Primary outcome: Primary: Subjective Response to Smoking Cigarettes From the Cigarette Evaluation Scale — 4.68; 4.50 score on a scale — p=>.05

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Cigarette flavor type (Other)
Age
Adult · 18+ yrs
Sex
All
Sponsor
University of Oklahoma
Primary completion
Dec 2022

Outcome Measures

OutcomeResultp-value
PRIMARY
Subjective Response to Smoking Cigarettes From the Cigarette Evaluation Scale
4.68; 4.50 >.05
PRIMARY
Average Daily Subjective Response From Smoking
1.68; 1.79 >.05
PRIMARY
Highest Trial Competed for a Menthol Cigarette Puff in the Choice Task (Relative Reinforcing Value for Menthol Cigarettes)
9.2; 0.83 <.05 sig
PRIMARY
Past 30-day Cigarette Smoking Frequency
20.8; 20.7 <.05 sig
PRIMARY
Puff Topography
18.7; 18.4 >.05
SECONDARY
Number of Clicks for Menthol Cigarette Puffs on the Behavioral Choice Task
1244.56; 104.11 <.05 sig
SECONDARY
Quantity of Past 30-day Tobacco Product Use
1.3; 2 <.05 sig
SECONDARY
Number of Participants With Intentions to Smoke Menthol Cigarettes
16 >.05
SECONDARY
Cigarettes Per Day
9.9; 9.5 >.05
SECONDARY
Average Daily Craving From Smoking
1.55; 1.53 >.05

Summary

This study focuses on menthol (n = 125) and non-menthol (n = 125) smoking young adults (YAs; defined here as ages 18 to 26).

Eligibility Criteria

Inclusion Criteria

  • Ages 18-26
  • Currently smoke cigarettes "everyday" or "somedays"
  • A strong preference for menthol or non-menthol cigarettes
  • able to read and understand the consent form
  • willingness to abstain from nicotine or tobacco products for at least 12 hours prior to smoking sessions

Exclusion Criteria

  • Current use of nicotine replacement therapy
  • Pregnant or planning to become pregnant; or breastfeeding
  • self-reported diagnosis of lung disease, including asthma, cystic fibrosis, or chronic obstructive pulmonary disease; or
  • self-reported history of cardiac event or distress within the past 3-months
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03953508). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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