N/A N=139 Cigarette Smoking Among Young Adults
Cigarette Smoking · Smoking Behaviors
Primary: Puff Topography — 1108; 1045.2; 1084.6 mL
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=40 Acute Effects of Cigarette Packaging and Charcoal Filtration on Perceptions, Use Behaviors, and Harm Exposure
Smoking Behaviors
Primary: Number of Puffs Taken (Video-scored Smoking Behavior Outcome 1) — 15.8; 16.7; 19.1; 19.6 puffs
N/A N=199 Perceptions of Cigarette Smoking in Young Adults
Smoking, Cigarette
Primary: Subjective Response to Smoking Cigarettes From the Cigarette Evaluation Scale — 4.68; 4.50 score on a scale — p=>.05
N/A N=31 Impact of Exclusive Use of Low Nicotine Cigarettes on Compensatory Smoking
Smoking
Primary: Breath Sample (Expired Carbon Monoxide) — 18.77; 31.07; 25.38; 30.49 parts per million — p=0.92
N/A N=80 Low Nicotine Cigarettes Plus Electronic Cigarettes
Tobacco Dependence
Primary: Urinary NNAL (4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol) — 505.6; 459.1; 373.3; 180.5 pg/mg creatinine — p=0.017
N/A N=31 Cigarette Smoking in Smokers With and Without Schizophrenia
Tobacco Dependence · Schizophrenia
Primary: End-of-session Carbon Monoxide — 62.7; 43.0 parts per million (ppm)
N/A N=36 Palatability of Experimental Cigarettes - Study 2
Smoking
Primary: Change in UrineTotal Nicotine Equivalent (TNE) Between Baseline and Week 1 — -16.2; -7.6; 1.3 nmols/ml
N/A N=136 Reduced Nicotine Content Cigarettes and Tobacco Switching Behaviors
Tobacco Addiction · Dual Tobacco Use
Primary: Number of Days Using Alternative Products — 14; 26; 20 Number of days
N/A N=30 Sugars in Cigarettes
Tobacco Use
Primary: Impact of Cigarette Sugar Content on Product Satisfaction. — 4.09; 3.89; 3.92; 4.39 units on a scale
N/A N=37 Cigarette Smoking Decision Study
Tobacco Smoking
Primary: Demand Intensity as Assessed by a Behavioral Economic Demand Curve — 4.709677419; 2.580645161 puff bouts
N/A N=387 Cigarette Pack Inserts for Smoking Cessation
Smoking Cessation
Primary: Self-efficacy to Quit Smoking — 2.61; 2.76; 2.62; 2.56 score on a scale — p=0.60
N/A N=60 Smoking Topography and Harm Exposure in Menthol Cigarettes
Cigarette Smoking Toxicity
Primary: Smoking Topography- Puff Volume — 518; 661; 650; 620 mL
N/A N=213 Very Low Nicotine Content Cigarettes and E-Cigarettes in Promoting Smoking Cessation in Daily and Intermittent Cigarette Smokers
Cigarette Smoking-Related Carcinoma · Tobacco-Related Carcinoma
Primary: Usual Brand Cigarettes Per Day — 15.803; 2.1563; 1.8353; 1.4931 Cigarettes per Day
N/A N=75 Self-Control and Adult Cigarette Smokers
Smoking
Primary: Self- Control as Measured by the Change in the Length of Time Participants Can Hold a Hand-grip at Baseline and Follow-up (One Week After Baseline) — -9.36; 2.76; -4.32…
N/A N=50 Project 2 Cigarette and E-cigarette Nicotine Content and E-liquid Flavors
Smoking
Primary: Total Cigarettes Smoked Per Day — 21.6; 7.7; 18.4; 12.5 number of cigarettes
N/A N=64 Cigarette and E-cigarette Nicotine Content in an Electronic Tobacco Marketplace (ETM)
Tobacco Use
Primary: Number of Cigarettes Purchased — 154.7; 119.2 average number of cigarettes
N/A N=22 Comparative Abuse Liability Among African American and White Smokers
Tobacco Use Disorder
Primary: Nicotine Delivery — 14.13; 6.79; 9.15 ng/mL — p=0.002
N/A N=22 Assessment of Two New Electronic Cigarettes in Cigarette Smokers
Electronic Cigarettes
Primary: Change in Plasma Nicotine — 7.62; 10.65; 18.31; 7.19 ng/ml
N/A N=326 Low Nicotine Content Cigarettes in Vulnerable Populations: Women of Reproductive Age
Tobacco Use Disorder
Primary: Number of Cigarettes Smoked Per Day — 22.54; 14.32; 11.76; 7.63 cigarettes per day
N/A N=1,132 Correcting Public Misperceptions About Very Low Nicotine Content Cigarettes
Tobacco Use, Cigarette Use
Primary: Very Low Nicotine Content (VLNC) Misperception — 3.12; 3.04; 3.04; 3.36 score on a scale
N/A N=35 Low Nicotine Cigarettes, Smoking, and Chronic Pain
Chronic Pain · Smoking, Cigarette
Primary: Cigarettes Smoked Per Day — 14.5; 17.2; 16.4; 20.3 cigarettes/day — p=<.0001
N/A N=5 Effects of Smoking State on Decision Making
Behavior
Primary: Effort Based Decision Making — 29.5; 18.3 high effort selections
N/A N=184 Brain Nicotine Receptor Density in Veteran Smokers
Positron Emission Tomography
Primary: PET Scan, Rating Scales — 7.1; 8.6; 7.9; 8.0 Vt/fp or mL/cm3
Phase 2 N=95 Smoking, Sex Hormones, and Pregnancy
Nicotine Dependence · Contraception
Primary: Change in Smoking Urges — 5.0; 5.5 score on a scale
N/A N=33 Impact of Switching to Non-Menthol Cigarettes Among Smokers
Tobacco Use
Primary: Total Number of Cigarettes Smoked — 2.2 cigarettes per day
N/A N=2,896 Smoking Cessation Self-Help for Dual Users of Tobacco Cigarettes and E-Cigarettes
Smoking Cessation
Primary: Rate of Smoking Abstinence — 33; 40; 37; 42 percentage of participants
N/A N=238 Very-Low Nicotine Cigarettes and Non-Daily Smokers
Smoking
Primary: Change in Cigarette Consumption — -1.6; -0.05 cigarettes per day — p=<0.001
N/A N=25 Nicotine Pharmacokinetic Study of Heated Tobacco and Heated Herbal Products
Healthy Volunteers
Primary: Nicotine Cmax — 13.00; 12.97; 6.00; 6.87 ng/mL
Phase 4 N=179 Smoking Tobacco and Drinking Study
Smoking · Heavy Episodic Drinking
Primary: Number of Participants With Reported 7-day Point Prevalence Abstinence at 3 Months — 3; 4 Participants
N/A N=30 Quit or Switch: E-cigarette Study
Tobacco Use
Primary: Percentage of Participants Who Report Daily Use of E-cigarettes or NRT and no Cigarette Use