N/A N=31 Randomized Treatment

Tracking Depression Symptoms With a Health Chatbot

Depression, Postpartum · Depression, Unipolar

Bottom Line

View on ClinicalTrials.gov: NCT03990389 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

May 2022

Primary outcome: Primary: Longitudinal Change in Depression Severity — 16.13; 14.06; 10.47; 10.69 score on a scale — p=0.0618

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Chatbot Intervention (Device)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: University of Chicago
Primary completion: Feb 2020

Outcome Measures

Outcome	Result	p-value
PRIMARY Longitudinal Change in Depression Severity	16.13; 14.06; 10.47; 10.69; 8.23; 11.35	0.0618
SECONDARY Change in Depression Severity	-6.2; -3.1	0.116
SECONDARY Change in Side-effect Burden	—	—
SECONDARY Change in Maternal Function	—	—
SECONDARY Change in Maternal Confidence	—	—
SECONDARY Medication Adherence	—	—

Summary

The goal of this research is to bridge a significant "effectiveness" gap in the treatment of depression. The investigators have developed a chatbot which will assist in performing measurement-based care (MBC) via Facebook Messenger. Participants will be randomized to either Usual Care or Usual Care with additional Chatbot Care.

Eligibility Criteria

Inclusion Criteria

Provider Subject Cohort: residents and attendings from University of Chicago Medical Center OBGYN and NorthShore Hospital OBGYN clinics.
Patient Subject Cohort:
Age ≥ 18 years and able to and demonstrate English reading literacy of at least 8th-grade level (REALM-R ≥ 6)
Postnatal women newly diagnosed or receiving treatment for non-psychotic unipolar depression with a severity-based entry criterion of moderate to severe (EPDS ≥ 12)
Willing to participate and able to give written informed consent
Must own a smart phone with a data plan
Must have a Facebook account and Facebook Messaging app on phone (or willing to create account/download app today)
Sufficient cognitive ability to provide self-report data on a computer touchscreen/ standard computer with minimal assistance

Exclusion Criteria

Provider Subject Cohort: None
Patient Subject Cohort:
Subjects with documented dysthymia or Axis II diagnoses
Subjects with self-reported or documented history of: anorexia or bulimia, obsessive compulsive disorder or prior hospitalization for suicidal ideation
Active suicidality as determined by clinician
Non-English speakers

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03990389). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.