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N/A N=385 Randomized Single-blind Treatment

Improving the Academic Performance of First-Grade Students With Reading and Math Difficulty

Reading Learning Disability · Math Learning Disability

Enrolled (actual)
385
Serious AEs
0.0%
Results posted
Mar 2026
Primary outcome: Primary: Word Reading Fluency-2 (Zumeta et al., 2012) — 10.216; 7.068; 12.349; 7.385 words read correctly — p=.018

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Reading Intervention (Behavioral); Math Intervention (Behavioral); Coordinated Intervention (Behavioral)
Age
Pediatric · 6+ yrs
Sex
All
Sponsor
Vanderbilt University
Primary completion
May 2025

Outcome Measures

OutcomeResultp-value
PRIMARY
Word Reading Fluency-2 (Zumeta et al., 2012)
10.216; 7.068; 12.349; 7.385 .018 sig
PRIMARY
Sight Word Efficiency (TOWRE2; Wagner et al., 2012)
17.567; 14.405; 19.630; 14.718 <.001 sig
PRIMARY
Woodcock-Johnson IV - Letter Word Identification (Woodcock-Johnson 2014).
24.284; 21.459; 26.616; 21.756 <.001 sig
PRIMARY
Arithmetic Combinations Fluency (Fuchs et al., 2003)
11.269; 15.014; 6.849; 6.269 <.001 sig
PRIMARY
Double-Digit Calculations Fluency (Fuchs et al., 2003)
6.284; 8.649; 0.740; 1.038 <.001 sig
PRIMARY
Woodcock-Johnson IV - Calculations (Woodcock-Johnson 2014)
13.090; 13.811; 10.795; 9.679 <.001 sig

Summary

The main purpose of this clinical trials is to explore short-term effects of coordinated intervention versus the business-as-usual school program on the primary endpoints of post-intervention word-reading fluency and arithmetic fluency. The study population is students who begin 1st grade with delays in word reading and calculations. Students who meet entry criteria are randomly assigned to coordinated intervention across reading and math, reading intervention, math intervention, and a business-as-usual control group (schools' typical program). The 3 researcher-delivered interventions last 15 weeks (3 sessions per week; 30 minutes per session). Students in all 4 conditions are tested before researcher-delivered intervention begins and after it ends.

Eligibility Criteria

Inclusion Criteria

  • Attends a participating school in the Metropolitan-Nashville Public Schools
  • Is a member of a first-grade classroom whose teacher has agreed to let his/her students participate
  • Has the available school schedule to participate
  • Has adequate English proficiency to be reliably assessed in English on study entry screening measures
  • Scores at or below the 25th percentile on the study's screening math test
  • Scores at or below the 25th percentile on the study's screening reading test
  • Scores at or above the 7th percentile on at least one of the study's two measures of cognitive performance

Exclusion Criterion:

  • Does not attend a participating school in the Metropolitan-Nashville Public Schools
  • Is not a member of a first-grade classroom whose teacher has agreed to let his/her students participate
  • Does not have the available school schedule to participate
  • Does not have adequate English proficiency to be reliably assessed in English on study entry screening measures
  • Scores above the 25th percentile on the study's screening math test
  • Scores above the 25th percentile on the study's screening reading test
  • Scores below the 7th percentile on both of the study's two measures of cognitive performance
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03991234). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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