Phase 3
Completed N=78
ESP Block VS TAP in Laparoscopic Hysterectomy
Source: ClinicalTrials.gov NCT04003987 ↗Enrolled (actual)
78
Serious AEs
0.0%
Results posted
Jul 2022
Primary outcomePrimary: Visual Analogue Scale (VAS) Pain Scores at Rest at 1 Hour. — 2.8; 3 score on a scale
◆ Published Evidence
Highly cited
371citations · ~53 / year
The erector spinae plane (ESP) block: A pooled review of 242 cases.
Summary
The purpose of this study is to compare the difference between two different pain control methods in patients who will be having a hysterectomy surgery. By collecting this data, we aim to show improved postoperative pain scores, decreased opioid needs, and decreased opioid side effects (nausea, sedation, ileus, urinary retention, respiratory depression).
Linked Publications (5)
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The erector spinae plane (ESP) block: A pooled review of 242 cases.
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Transversus Abdominis Plane Block for Post Hysterectomy Pain: A Systematic Review and Meta-Analysis.
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Estimating the Effect of Intravenous Acetaminophen for Postoperative Pain Management on Length of Stay and Inpatient Hospital Costs.
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Erector spinae plane block for postoperative analgesia in laparoscopic cholecystectomy: a case report.
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Local injection of liposomal bupivacaine combined with intravenous dexamethasone reduces postoperative pain and hospital stay after shoulder arthroplasty.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Visual Analogue Scale (VAS) Pain Scores at Rest at 1 Hour. |
2.8; 3 | — |
| PRIMARY Visual Analogue Scale (VAS) Pain Scores at Rest at 24 Hours. |
3; 2.8 | — |
| PRIMARY Visual Analogue Scale (VAS) Pain Scores at Rest at 48 Hours. |
2.1; 2 | — |
| PRIMARY Visual Analogue Scale (VAS) Pain Scores With Movement at 1 Hour. |
3; 3.5 | — |
| PRIMARY Visual Analogue Scale (VAS) Pain Scores With Movement at 24 Hours. |
4.3; 4.1 | — |
| PRIMARY Visual Analogue Scale (VAS) Pain Scores With Movement at 48 Hours. |
3.4; 3.2 | — |
| SECONDARY Patient Sedation Score at 1 Hour |
15; 15; 23; 24 | — |
| SECONDARY Patient Sedation Score at 24 Hours |
2; 1; 34; 38 | — |
| SECONDARY Patient Sedation Score at 48 Hours |
0; 1; 35; 38 | — |
| SECONDARY Patient Nausea Score at 1 Hour |
5; 6; 33; 33 | — |
| SECONDARY Patient Nausea Score at 24 Hour |
11; 7; 25; 32 | — |
| SECONDARY Patient Nausea Score at 48 Hour |
2; 7; 33; 32 | — |
| SECONDARY Patient Satisfaction Score at 24 Hours |
3.7; 3.6 | — |
| SECONDARY Patient Satisfaction Score at 48 Hours |
3.7; 3.7 | — |
Eligibility Criteria
Inclusion Criteria
- Patients undergoing laparoscopic hysterectomy surgery at Indiana University Hospital
- ASA class 1, 2, 3 or 4
- Age 18 or older, female
- Desires Regional anesthesia for postoperative pain control
Exclusion Criteria
- History of substance abuse in the past 6 months.
- Patients on more than 30 mg morphine equivalents of opioids.
- Any physical, mental or medical conditions which in the opinion of the investigators, may confound quantifying postoperative pain resulting from surgery.
- Known allergy or other contraindications to the study medications (Acetaminophen, Gabapentin, Bupivacaine).
- Postoperative intubation.
- Any BMI greater than 40.0.
Data sourced from ClinicalTrials.gov (NCT04003987) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.