N/A N=33

Enhanced, Personalized and Integrated Care for Infection Management at the Point-Of-Care

Antibiotic Resistant Infection · Infection

Bottom Line

View on ClinicalTrials.gov: NCT04013737 ↗

Enrolled (actual)

Serious AEs

—

Results posted

Aug 2021

Primary outcome: Primary: Percentage of Appropriate Antimicrobial Prescriptions Recommended — 90 percentage of prescriptions appropriate

Study Design & Population

Study type: Observational
Phase: N/A
Interventions: EPIC IMPOC (Device)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Imperial College London
Primary completion: Aug 2019

Outcome Measures

Outcome	Result	p-value
PRIMARY Percentage of Appropriate Antimicrobial Prescriptions Recommended	90	—
PRIMARY Evaluation of Effectiveness Assessed by User Acceptance of the Device	3; 10	—

Summary

Antimicrobials (drugs that kill or stop the growth of microorganisms including bacteria, thereby treating infections) commonly used to treat patients with infections are becoming less effective over time as bacteria develop resistance to them. Antimicrobial usage itself can lead to development and spread of antimicrobial resistance. Antimicrobial resistance is now a major threat to patient safety. To conserve the effectiveness of antimicrobials the investigator need to develop ways to use them more sensibly healthcare professionals who diagnose and treat infections must be able to access antimicrobial guidelines and test results at the patient bedside. This needs to be provided rapidly and with support to make sure that the decisions on prescribing antimicrobials are the best that can be made.

Eligibility Criteria

Inclusion Criteria

(i) healthcare professionals for evaluation phases: Have read the PIL and consent to participate in the study

(ii) patients for whom the clinician chooses to use the POC DSS as a resource when prescribing antimicrobials: Adult patients > 18 years old Being managed for infection outside of the critical care setting in Imperial College Healthcare NHS Trust Deemed appropriate for management with POC DSS by attending physician Prescribed antimicrobial agents outside of the critical care setting in last 5 days

(iii) Prescriber / healthcare professional for using POC DSS: Trained Healthcare Professional Working within wards under assessment Deemed suitable for recruitment by senior member of their team

Exclusion Criteria

(i) healthcare professionals: Do not wish to participate in the study Working across wards which is acting as a control ward Deemed no suitable for recruitment by a senior member of their team Non-permanent member of the Trust Information governance training not up-to-date

(ii) patients recruits Critical care patients Paediatric patients < 18 years old Deemed not suitable for management using POC DSS by attending physician On palliative care, end of life pathway Prisoners / young offenders in custody of HM Prison Service Involved in current research or have recently been involved in any research prior to recruitment (last 3 months)

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Data sourced from ClinicalTrials.gov (NCT04013737). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.