HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Drug Pipeline
Sys. Review
Narrative review on PCSK9 inhibitors for familial hypercholesterolemia
Review explores PCSK9 inhibitors for familial hypercholesterolemia
This narrative review synthesizes evidence on PCSK9 inhibitors, including evolocumab, for familial hypercholesterolemia. The authors discuss…
This review looks at PCSK9 inhibitors like evolocumab for people with familial hypercholesterolemia. It discusses how these drugs work and t…
Frontiers
May 27, 2026
Allergy & Immunology
Sys. Review
Molecular review explores Siglec signaling pathways in cancer and inflammatory disorders
Siglec proteins help immune system balance fighting disease and avoiding self-harm
This molecular review examines the role of Siglec signaling pathways in human biology. The authors discuss potential therapeutic opportuniti…
Siglec proteins act as brakes on immune cells, and targeting them could help treat cancer and autoimmune disorders.
Frontiers
May 21, 2026
Infectious Disease
Meta-analysis
Meta-analysis shows association between adequate antimicrobial therapy and reduced hospital length of stay
Right Antibiotic Choice Cuts Hospital Stay by Nearly Two Weeks
This meta-analysis of 4158 adult hospitalised patients examines the relationship between adequate empirical antibiotic therapy and clinical …
Choosing the right antibiotic from the start can cut a hospital stay by nearly two weeks for adults with serious infections.
May 2, 2026
Diabetes & Endocrinology
Observational study links PADI4 haplotypes to wound healing and infection risk in diabetes
Diabetes Wound Healing Tied to Hidden Gene Variant
This abstract from an observational study in 687 surgical patients (44.7% with diabetes) found that minor PADI4 haplotypes are associated wi…
A gene variant linked to excessive immune traps raises infection and slow-healing risk in diabetes patients.
medRxiv
Apr 28, 2026
Drug Pipeline
Meta-analysis
Systematic review synthesizes Rhaponticum species chemistry, traditional uses, and research gaps across multiple conditions
Ancient Herbs May Help Modern Health
This systematic review synthesizes data on Rhaponticum species, covering 24 documented species worldwide and their applications for conditio…
Imagine walking through a garden filled with wildflowers.
Frontiers
Apr 24, 2026
Drug Pipeline
Sys. Review
Integrative review of Tedania sponge compounds for cancer and infections
Sponge Compounds May Fight Cancer and Infections, Study Suggests
This integrative review synthesizes evidence on 135 compounds from Tedania marine sponges for cancer, inflammatory diseases, and microbial i…
Marine sponges are a rich source of natural compounds that could one day lead to new treatments for cancer and infections, but more research…
Frontiers
Apr 24, 2026
Emergency Medicine
Prospective observational study of inflammatory mediators in adult ED patients with suspected infection
Blood protein patterns in sick ER patients hint at who might survive
This primary prospective, observational study in a single-centre Emergency Department measured longitudinal inflammatory mediators in 173 ad…
In ER patients with suspected infection, certain blood proteins changed over time and linked to survival, offering clues for future monitori…
medRxiv
Apr 21, 2026
Infectious Disease
Cohort
In ICU-infected patients, metagenomic next-generation sequencing showed higher positive detection rates than conventional microbiological testing
A Single Test Could Finally Unravel Your Body’s Hidden Infection Battle
This retrospective cohort study evaluated 156 ICU-infected patients comparing metagenomic next-generation sequencing (mNGS) to conventional…
For patients fighting severe infections in the ICU, a powerful new type of test can quickly identify the enemy, its weapons, and the body’s …
Frontiers
Apr 11, 2026
Psychiatry
Meta-analysis
Protocol outlines systematic review of IPC measures in long-term care facilities
How do infection control measures affect life and costs in nursing homes?
This protocol describes a planned systematic review of infection prevention and control measures in long-term care facilities.
Nursing homes face tough choices about infection control measures that impact resident safety, quality of life, and facility costs.
Frontiers
Apr 3, 2026
Neurology
Meta-analysis
Systematic review links elevated bilirubin and infections to hearing loss in NICU neonates
What clues in a newborn's body might signal future hearing problems?
A systematic review and meta-analysis of 86 studies in NICU neonates found elevated bilirubin exposure and infective conditions were consist…
High bilirubin levels and serious infections like meningitis are linked to hearing loss in newborns, but study quality varies.
Frontiers
Apr 2, 2026
Infectious Disease
Sys. Review
Systematic review details metabolic adaptations of intracellular bacterial pathogens within host cells
How do bacteria hide inside our cells to survive and cause disease?
A systematic review synthesized evidence on how intracellular bacterial pathogens, including Listeria and Chlamydia species, employ sophisti…
Bacteria like Listeria and Chlamydia act as metabolic thieves, stealing nutrients from our cells to hide from our immune system and survive.
Frontiers
Apr 1, 2026
Questions about Infections
Does getting enough antibiotics help patients with infections leave the hospital sooner?
Getting enough appropriate antibiotics significantly shortens hospital stays for infections, with adequate therapy reducing average stay by about 1.2 days compared to inadequate treatment.
Full answer →Can high bilirubin levels and infections cause hearing loss in newborns in the NICU?
Yes, high bilirubin levels and certain infections like cytomegalovirus are established risk factors for hearing loss in newborns in the NICU.
Full answer →How does adequate antibiotic therapy affect hospital length of stay for infections?
Adequate antibiotic therapy significantly shortens hospital stays for infections, reducing the average length of stay by about 1.17 days compared to inadequate treatment.
Full answer →