N/A
Completed N=483
Presessions for the National Diabetes Prevention Program
Source: ClinicalTrials.gov NCT04022499 ↗Enrolled (actual)
483
Serious AEs
—
Results posted
Sep 2025
Primary outcomePrimary: Weight Loss — 3.1; 2.8 % of weight loss
Summary
The National Diabetes Prevention Program (NDPP) is a widely available, evidence-based intervention that promotes weight loss to prevent type 2 diabetes; however, participant attendance is problematic and leads to suboptimal weight loss, especially among Hispanic, non-Hispanic black, and low-income non-Hispanic white participants. An innovative pre-session enhancement to the NDPP (Pre-NDPP) showed successful results upon initial application in a diverse and predominately low-income population, with doubled attendance and weight loss outcomes as compared to previous NDPP participants who did not receive a pre-session. If Pre-NDPP is shown to be successful upon more rigorous study, it can be widely adopted by NDPP providers across the country to help reduce diabetes prevalence and related health disparities.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Weight Loss |
3.1; 2.8 | — |
Eligibility Criteria
Inclusion Criteria
- Denver Health patients
- BMI≥25 (≥23 if Asian)
- History of recent prediabetes or former gestational diabetes (GDM) diagnosis (patients without known prediabetes or past GDM may also be eligible based on a risk screening tool)
Exclusion Criteria
- Pregnant at enrollment
- Known to have diabetes
- Non-English or non-Spanish-speaking.
Data sourced from ClinicalTrials.gov (NCT04022499). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.