N/A
Completed N=5
Neurological Impacts of Artificial Sweeteners in the Context of Diet Sodas
Source: ClinicalTrials.gov NCT04048681 ↗Enrolled (actual)
5
Serious AEs
0.0%
Results posted
Feb 2020
Primary outcomePrimary: Changes in Brain Response to Food Cues in the Insula — 0.25; -0.9; -0.01 z-score
Summary
This study seeks to determine whether artificial sweeteners in the context of diet soda may alter the brain's response to food cues and thus impact appetite.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Changes in Brain Response to Food Cues in the Insula |
0.25; -0.9; -0.01 | — |
| SECONDARY Neurocognitive Testing (Stop Signal Reaction Time) |
162.6; 172.9; 180.2 | — |
Eligibility Criteria
Inclusion Criteria
- Men and women who are 18-65 years old, with a BMI >30kg/m2.
Exclusion Criteria
- Unable or unwilling to participate in the study for any reason
- Metal in the body or other safety concerns which makes patient unable to have an MRI
- Pregnant women will be excluded to protect the fetus against potential effects of a non-medically required MRI on fetal development and difficulty of measuring accurate BMI.
Data sourced from ClinicalTrials.gov (NCT04048681). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.