N/A
N=42
Attachment and Biobehavioral Catch-up for Depression
Depressive Symptoms · Anxiety Symptoms
Bottom Line
View on ClinicalTrials.gov: NCT04050202 ↗Enrolled (actual)
42
Serious AEs
0.0%
Results posted
Jul 2024
Primary outcome: Primary: Change From Baseline in Internalizing Subscale Score of the Child Behavior Checklist (CBCL) at Week 10 (Value at Baseline Minus Value at Post Intervention (Week 10)) — 8.5 units on a scale — p=<0.01
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Attachment and Biobehavioral Catch-up (ABC) Intervention (Behavioral)
- Age
- Adult · 18+ yrs
- Sex
- Female
- Sponsor
- University of California, San Francisco
- Primary completion
- Sep 2022
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change From Baseline in Internalizing Subscale Score of the Child Behavior Checklist (CBCL) at Week 10 (Value at Baseline Minus Value at Post Intervention (Week 10)) |
8.5 | <0.01 sig |
| PRIMARY Change From Baseline in Center for Epidemiologic Studies-Depression Scale (CES-D) at Week 10 (Value at Baseline Minus Value at Post Intervention (Week 10)) |
12.6 | <0.01 sig |
Summary
The overarching goal is to pilot the Attachment and Biobehavioral Catch-up (ABC) intervention for mothers with heightened depressive symptom and their children with heightened internalizing symptoms.
Eligibility Criteria
Inclusion Criteria
- Mothers between 18 and 50 years of age with heightened depressive symptoms as determined by a score of 16 or higher on the Center for Epidemiologic Studies Depression Scale-Revised (CESD-R)
- Biological children (of mothers described above) between 2 and 4 years old with heightened internalizing symptoms as determined by a T-score of 60 or higher on the Childhood Behavior Checklist (CBCL)
Exclusion Criteria
- Self-reported history of psychosis or active suicidality as defined by self-report of a specific suicide plan or recent attempt
- Current pregnancy
- Child diagnosis of autism
- Pacemaker implant, cardiac problems, cardiac medication
Data sourced from ClinicalTrials.gov (NCT04050202). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.