N/A
N=71
Yoga and Aerobic Exercise Effects on Cognition
Stress, Psychological
Bottom Line
View on ClinicalTrials.gov: NCT04077645 ↗Enrolled (actual)
71
Serious AEs
0.0%
Results posted
Aug 2025
Primary outcome: Primary: N-back Task (Working Memory) — 827.50; 844.26; 832.60 Milliseconds
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Sun salutations (Behavioral); Aerobic exercise (Behavioral); Seated rest (Behavioral)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of Illinois at Urbana-Champaign
- Primary completion
- Mar 2020
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY N-back Task (Working Memory) |
827.50; 844.26; 832.60 | — |
| SECONDARY Trail Making Test A and B (Global Cognition) |
43.21; 39.18; 40.72 | — |
| SECONDARY Digit Symbol Substitution Test (Processing Speed) |
108.52; 116.23; 120.71 | — |
| SECONDARY State Trait Anxiety Questionnaire |
30.04; 35.95; 36.00 | — |
| SECONDARY Visual Analog Scale for Stress |
21.08; 28.82; 38.21 | — |
| SECONDARY Perceived Mental Fatigue |
1.87; 2.01; 2.29 | — |
| SECONDARY Focus of Attention |
7.84; 2.73; 5.42 | — |
| SECONDARY Feeling Scale |
3.68; 2.55; 3.21 | — |
| SECONDARY Heart Rate |
100.24; 119.27; 69.63 | — |
| SECONDARY Rating of Perceived Exertion |
11.24; 11.73; 7.63 | — |
| SECONDARY Rating of Enjoyment and Intervention |
.74 | — |
| SECONDARY Rating of Technology Ease of Use and Usability |
5.87 | — |
Summary
The purpose of this acute randomized control study is to assess the feasibility of a low-to-moderate intensity Yoga intervention (i.e. sun salutations), and examine its effect on cognitive functioning, compared to engaging in aerobic activity or seated rest. Participants will include individuals who are currently experiencing symptoms of psychosocial stress or general anxiety.
Eligibility Criteria
Inclusion Criteria
- Anyone between the ages of 18-45 years
- Anyone with a score of 3 or higher on the Generalized Anxiety Disorder symptom checklist of the Diagnostic and Statistical Manual 5. That is, anyone meeting 3 or more symptoms, on more days of the week than not, for the past 6 months:
- Restlessness, feeling keyed up or on edge. 2. Being easily fatigued. 3. Difficulty concentrating or mind going blank. 4. Irritability. 5. Muscle tension. 6. Sleep disturbance (difficulty falling or staying asleep, or restless, unsatisfying sleep).
- Ability to exercise at moderate to vigorous activity levels (defined as 50%-75% of the adjusted age-predicted maximum heart rate)
- Access to a smartphone and willingness to allow research staff to install a mobile activity tracker application (and space to allow for installation)
- Willingness to be randomized into one of three groups
Exclusion Criteria
- Anyone who is physically active (≥30 minutes, 2 or more times/week, for the last 3 months) and/or a regular practitioner of Yoga or mind-body activities (≥30 minutes, 2 or more times/week, for the last 3 months).
- Anyone with serious chronic medical conditions that would preclude them from participating without a physician present, or anyone with a risk of seizure, or anyone having psychiatric and/or neurological disorders.
- Anyone who does not consent to wearing the Fitbit, or does not have a smartphone that allows us to download an app on their phone.
- Pregnant women.
- Anyone incapable of performing the following movements at a moderate intensity- sitting, standing, kicking, pulling, pushing, bending one's elbows, bending the body forward, bending one's knees, lying down and getting up.
- Anyone with blood pressure of 200/105 or more, and anyone who scores 1 or more on the Physical Activity Readiness Questionnaire
- Anyone refusing or unwilling to be randomized into either of the conditions.
Data sourced from ClinicalTrials.gov (NCT04077645). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.